Biomedical subjects

Timothy A Salthouse

Publications and source records attributed to Timothy A Salthouse.

At least 19 recordsLinked to original sources

PubMed2006

Efficiency of route selection as a function of adult age.

Two tasks hypothesized to assess the efficiency of route selection were administered to 328 adults ranging from 18 to 93 years of age. Increased age was associated with slower completion of mazes, even after adjusting for differences in perceptual-motor speed, and with longer and less accurate routes in a task in which participants were asked to visit designated exhibits in a zoo. The route selection measures were correlated with measures hypothesized to represent executive functioning, such as the number of categories in the Wisconsin card sorting test and the number of words generated in a category fluency test. However, most of the age-related influences on the measures from the route selection tasks were shared with age-related effects on established cognitive abilities, which implies that the same mechanisms may account for the relations of age on both sets of variables.

Adolescent↗

PubMed2006

Short-term variability in cognitive performance and the calibration of longitudinal change.

Recent studies have documented that normal adults exhibit considerable variability in cognitive performance from one occasion to another. We investigated this phenomenon in a study in which 143 adults ranging from 18 to 97 years of age performed different versions of 13 cognitive tests in three separate sessions. Substantial within-person variability was apparent across 13 different cognitive variables, and there were also large individual differences in the magnitude of within-person variability. Because people differ in the amount of short-term variability, we propose that this variability might provide a meaningful basis for calibrating change in longitudinal research. Correlations among the measures of within-person variability were very low, even after we adjusted for reliability, and there was little evidence that increased age was associated with a larger amount of within-person variability.

Adolescent↗

PubMed2005

Is there anything special about the aging of source memory?

A battery of cognitive tests designed to measure the constructs of episodic memory, perceptual speed, fluid ability, executive functioning, and vocabulary was administered to 330 adults between the ages of 18 and 89. Each participant also performed 4 different tasks designed to assess source memory. Structural equation modeling was used to evaluate the validity of a source-memory construct and to explore the relation of the source-memory construct to age and to the other cognitive variables. The variance common to the source-memory variables was strongly related to other cognitive abilities, suggesting that source memory may not have discriminant validity, and there were only small unique age-related effects on the source-memory construct after the influence of other abilities was considered.

Adolescent↗

PubMed2005

Multivariate modeling of age and retest in longitudinal studies of cognitive abilities.

Longitudinal multivariate mixed models were used to examine the correlates of change between memory and processing speed and the contribution of age and retest to such change correlates. Various age- and occasion-mixed models were fitted to 2 longitudinal data sets of adult individuals (N>1,200). For both data sets, the results indicated that the correlation between the age slopes of memory and processing speed decreased when retest effects were included in the model. If retest effects existed in the data but were not modeled, the correlation between the age slopes was positively biased. The authors suggest that although the changes in memory and processing speed may be correlated over time, age alone does not capture such a covariation.

Age Factors↗

PubMed2005

Correlates of within-person (across-occasion) variability in reaction time.

A total of 420 adults between 18 and 91 years of age carried palm pilot (Palm M100; PalmOne, Milpitas, CA) devices and performed several reaction time trials when prompted at random times during the day. On the average, within-person variability in median reaction time from one occasion to the next was nearly the same magnitude as the between-persons variability in across-occasion mean reaction time. Analyses controlling the variation in one variable when examining relations involving the other variable suggested that an individual's mean reaction time is a more powerful predictor of relations with age and with the level of various cognitive abilities than his or her across-occasion SD.

Adult↗

PubMed2005

Relations between cognitive abilities and measures of executive functioning.

Although frequently mentioned in contemporary neuropsychology, the term executive functioning has been a source of considerable confusion. One way in which the meaning of a variable can be investigated involves examining its pattern of relations with established cognitive abilities. This method was applied to a variety of variables hypothesized to assess executive functioning in 2 data sets, 1 consisting of 328 adults between 18 and 93 years of age and a 2nd composite data set based on nearly 7,000 healthy adults between 18 and 95 years of age. Most of the hypothesized executive functioning variables were strongly related to reasoning and perceptual speed abilities, and very few had any unique relations with age after taking into consideration the relations of age through the cognitive abilities. These results raise questions about the extent to which neuropsychological tests of executive functioning measure a distinct dimension of variation in normal adults.

Adolescent↗

PubMed2004

Estimating retest effects in longitudinal assessments of cognitive functioning in adults between 18 and 60 years of age.

Several analyses were conducted on data from samples of adults between 18 and 58 years of age who completed the same cognitive tests after an interval ranging from less than 1 week to 35 years. Because the retest interval varied across individuals, it was possible to determine the length of time needed before the gains associated with a retest decreased to 0 and to obtain simultaneous estimates of the magnitude of effects associated with increased age and a prior assessment. The results indicated that for adults within this age range, 7 or more years were needed before positive retest effects were no longer detectable. Age effects in longitudinal comparisons could be interpreted in terms of large positive effects associated with a prior assessment and negative effects associated with age that were comparable in magnitude to those observed in cross-sectional comparisons.

Adolescent↗

PubMed2004

Modeling age and retest processes in longitudinal studies of cognitive abilities.

Mixed effects models were used to examine the separate effects associated with age and retest on changes in various cognitive abilities. Individuals (N > 800) ranging in age from 40 to 70 years at the 1st measurement occasion were assessed with measures of memory, spatial abilities, and speed on 4 occasions. All cognitive abilities showed decline associated with increased age and improvement across the 4 measurement occasions. The age-related effects were similar across variables, but the practice effects were largest for memory and smallest for speed. When retest effects were not included in the models, the age-related effects were underestimated, with the magnitude of bias depending on the size of the ignored retest effects. It is suggested that both age and retest should be modeled simultaneously when analyzing longitudinal data because part of the change across occasions may be attributable to practice or reactive effects.

Adult↗

PubMed2004

Methodological and theoretical implications of intraindividual variability in perceptual-motor performance.

As an individual differences variable, lability (within-person variability) has often been neglected even though it has been shown to predict key outcomes such as mortality. We examine intraindividual variability in perceptual-motor performance and relate it to chronological age in a sample of adults. The magnitude of between-session variability was found to average between 25% and 50% of the between-person variability and was equivalent in magnitude to the variation that was apparent across an age range of 12 to 27 years in cross-sectional comparisons. Age is related to the magnitude of intraindividual variability, which in turn is negatively related to performance on other cognitive tasks. Various implications of the findings are discussed.

Adult↗

PubMed2004

Construct validity and age sensitivity of prospective memory.

We administered four prospective memory tasks to 330 adults between 18 and 89 years of age to investigate the relationship among the measures of performance in the four tasks, as well as the relationship of the prospective memory measures to age, other cognitive abilities, and noncognitive factors. The four prospective memory variables were found to exhibit both convergent and discriminant validity, indicating that prospective memory ability appears to represent a distinct dimension of individual differences. The prospective memory construct was significantly related to other cognitive abilities, such as executive functioning, fluid intelligence, episodic memory, and perceptual speed, but it was only weakly related to self-ratings of (primarily retrospective) memory and to personality traits. Although a substantial proportion of the age-related variance on the prospective memory construct was shared with other cognitive abilities, we also found some evidence of unique, statistically independent, age-related influences on prospective memory.

Adolescent↗

PubMed2003

Executive functioning as a potential mediator of age-related cognitive decline in normal adults.

Critical requirements for the hypothesis that executive functioning is a potential mediator of age-related effects on cognitive functioning are that variables assumed to reflect executive functioning represent a distinct construct and that age-related effects on other types of cognitive functioning are reduced when measures of executive functioning are statistically controlled. These issues were investigated in a study involving 261 adults between 18 and 84 years of age. Although age-related effects on various cognitive abilities were substantially reduced after statistical control of the variance in measures hypothesized to represent executive functioning, there was only weak evidence for the existence of distinct constructs corresponding to executive functioning or to aspects of executive control concerned with inhibition, updating, or time sharing.

Adolescent↗

PubMed2003

What needs to be explained to account for age-related effects on multiple cognitive variables?

Structural equation methodology was used to investigate age-related influences across a number of cognitive variables in 204 adults ranging from 18 to 91 years of age with a hierarchical structure that contained 4 1st-order factors and 1 2nd-order common factor. Direct age relations were found to the common factor as well as to 1st-order speed and memory factors. Replicability of the findings was explored by investigating the same structure of age relations, using 2 different data sets, and a similar patten was found in each. These results suggest that at least 3 statistically distinct types of age-related influences are operating on a wide variety of cognitive variables and presumably require separate explanatory mechanisms.

Adolescent↗

PubMed2003

Assessing the age-related effects of proactive interference on working memory tasks using the Rasch model.

Inhibition-reduction theory (L. Hasher & R. Zacks, 1988) hypothesizes that the age-related decline in working memory (WM) span is a result of a decrease in the ability to inhibit irrelevant information in WM. Using the Rasch psychometric model, this study found that later trials on 2 WM span tasks were more difficult for older adults than for younger adults, consistent with inhibition-reduction theory's hypothesis that older adults are more susceptible to the effects of proactive interference (PI). Furthermore, after accounting for differential susceptibility to the effects of PI, age-related variance in WM span was reduced by about half. These results suggest that differential susceptibility to PI may account for a substantial portion, although not all, of the age-related decline in WM span.

Adolescent↗

PubMed2002

The role of cognitive stimulation on the relations between age and cognitive functioning.

To make a convincing argument that cognitive stimulation moderates age trends in cognition there must be (a) a negative relation between age and level of cognitive stimulation, (b) a positive relation between level of cognitive stimulation and level of cognitive functioning, and (c) evidence of an interaction between age and cognitive stimulation in the prediction of cognitive functioning. These conditions were investigated in a study in which 204 adults between 20 and 91 years of age completed an activity inventory and performed a variety of cognitive tasks. Only the 1st condition received empirical support, and, thus, the results of this study provide little evidence for the hypothesis that cognitive stimulation preserves or enhances cognitive functioning that would otherwise decline.

Adult↗

PubMed2002

Interpreting reaction time measures in between-group comparisons.

Although reaction time measures have been used extensively in many types of between-group comparisons, the assumptions and limitations of reaction time measurement are not always recognized. In this article we discuss three issues that should be considered when designing and interpreting comparisons involving reaction time. These concern speed-accuracy tradeoffs, methods of analyzing measures postulated to reflect specific processes, and methods for distinguishing group-related influences that are shared with other variables from those that are unique to a single variable.

Confounding Factors, Epidemiologic↗

PubMed2002

Aging and time-sharing aspects of executive control.

A particularly important aspect of executive functioning involves the ability to coordinate two simultaneous activities. The role of this aspect of executive functioning in adult-age differences in cognitive performance was examined in a study involving 150 adults between 20 and 91 years of age who performed the same visual-motor tracking task with three different primary tasks. The participants also performed several additional cognitive tasks that allowed examination of the relation of time-sharing efficiency to other types of cognitive functioning The results were consistent with the existence of a distinct time-sharing ability because the time-sharing costs in the three dual-task combinations were significantly correlated with one another but only weakly correlated with other cognitive variables. Increased age was associated with reductions in time-sharing ability, and greater efficiency in performing two tasks at once was associated with better performance on tasks assessing spatial, reasoning, and memory abilities. Although this pattern is what one would expect if executive processes contribute to age differences in cognitive functioning, the effects were smaller than those associated with a perceptual speed construct.

Aging↗

PubMed1998

Relation of task switching to speed, age, and fluid intelligence.

Two studies were conducted to investigate whether a meaningful task-switching construct could be identified and, if so, to determine how it was related to measures of higher order cognition and to adult age. Both studies revealed that measures of task switching were moderately correlated across different combinations of tasks and that a switching construct could be distinguished from a construct reflecting processing speed. The results of the 2nd study revealed that although the task-switching construct was related to age and to measures of episodic memory, inductive reasoning, and spatial visualization, most of the relations between the switching construct and both age and other measures of cognition were shared with other variables.

Adolescent↗

PubMedDate not supplied

Memory aging from 18 to 80.

Data from samples of adults selected to be representative of the U.S. population were examined to investigate issues related to the breadth and timing of age-related effects on memory and other cognitive functions. The results suggest that memory aging begins in early adulthood, that it overlaps with other aspects of cognitive aging, and that it can occur without accompanying increases in between-person variability. These findings imply that it is important to consider factors occurring early in life when attempting to understand the causes of memory and cognitive impairments apparent late in life.

Adolescent↗