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Biomedical subjects

U Brunner

Publications and source records attributed to U Brunner.

At least 55 records · Page 3Linked to original sources
PubMed1983

[Familial Mediterranean fever].

The diagnosis of familial Mediterranean fever is often difficult. The typical symptoms of this disease have been observed in two Turkish patients. The diagnostic criteria are short attacks of fever recurring in varying intervals, and painful symptoms in the abdomen, chest, joints or skin. Since no specific test for familial Mediterranean fever is available, the diagnosis must be based on precise clinical criteria and a genetic disorder with autosomal recessive inheritance and predilection for people of Mediterranean stock, particularly sephardic Jews and Armenians. The therapeutic response to colchicine may confirm diagnostic accuracy. Amyloidosis is a major symptom of the disease and dominates the further clinical picture. Treatment with dimethyl sulfoxide (DMSO) may inhibit the progression of amyloidosis and improvement of renal function can be achieved.

Adult↗
PubMed1983

Aplasia of superficial lymphatic capillaries in hereditary and connatal lymphedema (Milroy's disease).

Four patients with hereditary lymphedema present at birth (Milroy's disease) have been studied by fluorescence microlymphography (1, 7). The videomicroscopy technique failed to visualize any lymphatic capillary in the edematous part of their legs. In sporadic primary lymphedema with late manifestation, however, a well developed superficial capillary network is detected (1, 6). Three family members without lymphedema had normal microlymphatics. Milroy's disease, at least in the family presented, is characterized by aplasia or extreme hypoplasia of both lymphatic capillaries and collectors whereas in the usual sporadic form of primary lymphedema aplasia or hypoplasia is confined to the larger trunks.

Female↗
PubMed1982

[Vascular diseases in lipedema of the legs. Special symptoms, common therapeutic results, viewpoint on vascular surgery].

Lipedema of the legs is a symmetrical thickening of upper and lower leg and topically accentuated fat pads. The back of the foot is usually free of swelling. Pathogenetically it is a disturbance of the distribution pattern of subcutaneous fat tissue. Epidemiologically, the subjects affected are women, starting from puberty. Weight reduction programs do not influence the real deformations. If this abnormal fat tissue is infiltrated by angiological diseases, these manifest themselves in modified form. In particular, all the symptoms are more painful. In arterial ischemic syndromes that taut skin is susceptible to necrosis at atypical locations. For reconstruction of trunk arteries it is advisable to bypass larger bulges for better wound nealing. Venous strips should be peeled out away from fat pads and venous-bridges very carefully to protect the tissue. Acute and chronic phlebothrombosis lead to unusual and asymmetrical forms of swelling. The venous ulcer lies directly beneath a fat-muff in the gaiter region. Since they are hard to compress, free skin transplants should be considered early in the course of development. Surgery of varicose veins calls for most careful technique to ensure wound healing. From the lymphological viewpoint there are clinically and lymphographically mixed forms of lymphedema with lipedema.

Adipose Tissue↗