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Biomedical subjects

U Pandolfi

Publications and source records attributed to U Pandolfi.

At least 19 recordsLinked to original sources

[Inflammatory pseudotumor of the lung. Diagnostic-therapeutic effectiveness of its radical resection].

Clinical, therapeutical observations and experience in 3 cases of pulmonary inflammatory pseudotumors (PIP) are presented. A retrospective analysis is made of cases with pulmonary "mass" suspected as malignant tumor, resected in a general surgery department between 1988 and 1995, and finally diagnosed as inflammatory pseudotumor. Three of the 10 cases originally diagnosed as malignant lung tumor were inflammatory pseudotumor (30%). Pulmonary inflammatory pseudotumors, may be a pitfall diagnosing a lung mass and implicate legal problems. Surgical resection leads to the final diagnosis in doubtful cases. A wide resection has a diagnostic aim and may preserve healthy parenchyma. Clinicians, pathologists and surgeons should accurately inform patients with doubtful diagnosis of pulmonary malignancy. Any decision should be kept altogether either choosing the simple observation or the timely surgical diagnostic and therapeutical approach.

Diagnosis, Differential↗

[Malignant tumors of the small intestine. Clinical and therapeutic considerations on 23 observed cases].

Small bowel tumours observed by the Authors at the IInd Surgical pathology of Pavia University between 1974 and 1992 were reviewed. There were found 23 cases; istopathologic findings, clinical presentation, diagnostic aspects and therapeutic options are discussed. The primary role of surgery in the treatment of these cancers is emphasized, but this can be curative only if diagnosis has been timely.

Adenocarcinoma↗

[Validity of ano-rectal manometry in the diagnosis of cathartic colon as a cause of chronic pseudo-obstruction of the colon. Considerations on a case].

Cathartic colon is a rare pathology which hits old people and is radiologically characterized by dolichocolon and megarectum. It is nearly sure that the unusual length of the whole colon might be the first source of the cathartic disease. Rectal ampulla dilatation (megarectum) is due to the extended use of laxatives which induce changes in smooth muscle and in the myenteric nervous plexus. The anatomo-pathological changes of the rectum have been proved so far by histological examination of local and deep biopsy; now, in our opinion, they can be shown by manometry. The authors emphasize the possibility that cathartic colon might give episodes of diarrhoea and also recurrent bowel obstructions limited to the colon and so-called "chronic pseudo-obstruction" of the colon. They describe a case of this rare pathology admitted and treated in their ward. Gastric and esophageal motility in the patient was normal as was the motility of the upper rectum. Therefore they think that changes resulted from extended use of cathartics. In both cases patients show low manometric pressure, disordered peristalsis and in particular lack of internal anal sphincter relaxation in response to high balloon distension. As the occlusive status developed in an old patient (the patient was 81 years old), the authors think that the functional disorders were absent at birth. Cathartic colon is, in the authors experience, a cause of chronic pseudo-obstruction of the colon. Rectal manometry makes it possible to avoid surgical treatment. The therapy of pseudo-occlusion, if correctly diagnosed, consists in endoscopic intubation and decompression of the colon.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗

[Primary malignant lymphomas of the gastrointestinal system].

The Authors describe their experience regarding eight cases of primary malignant gastrointestinal lymphomas. After having briefly reexamined the epidemiology and the problems coming from the discordances that still exist on various systems of classification and of staging, they put in evidence that it is not always possible to reach a sure preoperative diagnosis on such pathology, and they explain some considerations about the diagnosis, the therapy and the prognosis.

Aged↗

[Synchronous and metachronous carcinoma of the large intestine].

The Authors report their experience about 20 cases of multiple large bowel adenocarcinomas, 9 of them synchronous and 11 metachronous. After developing a brief reexamination of epidemiology and etiopathogenesis, they explain their diagnostic and therapeutic considerations. The necessity of a real complete and exact radiological and endoscopical preoperative study, being also early, is at last emphasized, as well as an accurate postoperative follow-up.

Adult↗

[Lymphoma of the thyroid (description of 2 cases)].

Primary lymphoma of the thyroid is a rare disease and it occurs in a low percentage of thyroid tumours. Nevertheless its frequency is increasing. We present two observed cases in this study. One of these is an exceptional extra-nodal localization of Burkitt's lymphoma. The role of surgery in these particular neoplasms and the importance of intraoperative histological examination for the rational therapeutic behaviour are stressed.

Burkitt Lymphoma↗

[Rupture of the pancreas after closed injury of the abdomen (presentation of a case, clinical and therapeutic notes)].

The authors observed a case of a complete breaking of pancreas between head and body associated to a serious lesion of the liver, favourably treated in emergency by means of a subtotal splenopancreatectomy and a suture of the hepatic lacerations, and that gave them the occasion to think over the serious risks linked with an insufficient evaluation of a pancreatic lesion and its most appropriate surgical treatment. In details, personal experience and the examination of Literature showed that in the laparotomy it is absolutely necessary to examine all the gland carefully and methodically in order to recognize and evaluate accurately the pancreatic lesion, which is often concealed by the massive manifestations caused by the concomitant lesions of other intra-abdominal viscera. Besides, among the suggested surgical techniques, the subtotal splenopancreatectomy proved to be the safest, bringing no consequences from the functional point of view, even when extended to more than 80% of the glandular tissue.

Accidents, Traffic↗

[Torsion of the greater omentum (considerations apropos of 2 clinical cases)].

AA. refer 2 cases of great omentum torsion, of the secondary unipolar type, and of the primary type, chronic course and pelvic palpable mass appearance. After a short revision of pathogenesis and clinical features, AA. emphasize the difficulty almost impossibility of a proper preoperative diagnosis, in consideration too of the relative rarity of this pathology.

Adult↗

[Submucosal lipomas of the colon (considerations apropos of 3 clinical cases)].

Submucous colonic lipoma is relatively rare and can be the cause of important diagnostic and consequently therapeutic problems. The AA. reexamine the anatomo pathological and clinical features and the diagnostic and therapeutic problems, and refer 3 cases observed one of which was localized in the ileo-cecal valve. The AA. remark that radiological and endoscopic investigations and laparotomy features also can simulate a malignant tumor and address to the surgical technics of the oncologic surgery.

Aged↗

[Biliary perforations caused by acute pancreatitis: considerations apropos of a case of necrosis of the intrapancreatic choledochus caused by acute cephalopancreatitis secondary to a transduodenal sphincterotomy].

The AA. refear a case of massive necrosis of intrapancreatic biliary tract secondary to an acute necrotizing postoperative cephalopancreatitis. The high mortality lesion risk was successfully treated by many factors: surgicals and medicals. The AA. think that the wise use of Somatostatine was the most important factor.

Acute Disease↗

[Original operative technic in the surgical treatment of recto-sigmoid perforations (traumatic lesions, diverticular perforations, anastomotic dehiscences)].

In the modern rectal surgery the AA. think it be useful to preserve the sphinteric integrity to the greatest part of patients with non neoplastic rectosigmoid perforations (traumatic, diverticular, anastomotic leakage). They obtain to remove, by a personal modification, the difficulties and the disadvantages of intestinal restitution following the Hartmann's procedure.

Bacterial Infections↗

[Our surgical choice in the treatment of tumors of the rectum].

The AA. suggest to rationalise the criterion of choice in the operation of rectum tumour. According to the AA., the choice is between abdomino-perineal and anterior resection operation. In accordance with that acknowledgement and the respect of the precise oncological and anatomical presuppositions, they define the heart of the tumour and regulated their surgical conduct. In practice they perform the anterior resection for the tumours situated between the superior and inferior haemorrhoidal arteries which, after dissection, can be found at least 8-9 cm. from the anus, while they always deal with the abdomino-perineal the neoplasms which develop in the area of inferior and middle haemorrhoidal arteries.

Anus Neoplasms↗

[Case of isolated surgical lesion of the right hepatic duct].

A case of isolated surgical wound of the right hepatic duct is presented. Some considerations regarding all the pathogenetic, diagnostic and therapeutic problems are made. It is felt that, in this instance, surgical management was facilitated by the unusual length of the right hepatic duct, which terminated in the infundibulum of the gall bladder, due to a prior anatomical abnormality.

Bile Ducts, Intrahepatic↗