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Biomedical subjects

U Ruberto

Publications and source records attributed to U Ruberto.

25 records · Page 2Linked to original sources

[Long-term prognosis in monosymptomatic microscopic hematuria].

A group of 210 children, aged one to twelve years (86 males and 124 females) were sent to our Clinic with the diagnosis of microscopic hematuria. Twelve children in which microhematuria wasn't confirmed were immediately excluded; thirty children were excluded because they showed pathologic findings. The remaining 168 children were put under diagnostic examination (hematologic exams, urinoculture, abdomen radiographic, family screening). The cause of microhematuria was identified in 52 of them. The group was selected down to 116 who were then monitored for a period ranging from 1 to 9 years with periodical clinical and biohumoral controls and with diagnostic exams. Biopsies were performed only in 16 cases in which a nephropathy was suspected. Nine cases presented significant histological lesions. Seventy five children were subjected to observation for a period of over one year. After few years hematuria gradually disappeared in twenty six children. After nine years microhematuria had disappeared spontaneously in 39.9% of cases. It remained in core of 33.6% of case, for which no cause could be found. With reference to the full group of 168 children, the following pathologies have been found responsible of microhematuria: a) urinary way infections: 25 cases (14.8%) b) nephropathies: 16 cases (9.5%) c) familiar hematurias: 14 cases (8.3%) d) lithiasis: 9 cases (5.3%) e) alteration of the coagulation system: 3 cases (1.8%) f) renal hypercalciuria without lithiasis: 3 cases (1.8%) Based on these observation, we believe that careful waiting is the best tactic in the cases of monosymptomatic microhematuria.(ABSTRACT TRUNCATED AT 250 WORDS)

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[Results of 3 or 10 days' treatment with nitrofurantoin or cotrimoxazole in urinary infections in children].

110 children, affected by UTI, were included in this study; 52 of them were treated for 10 days and the remaining 58 for 3 days. Both groups were treated with cotrimoxazole or nitrofurantoin. Urine cultures were repeated soon after the end of therapy and repeated subsequently for a period of 6 months or of 1 year. There is not a great difference between the results obtained with the 10 days treatment and those of the 3 days treatment. An high percentage of relapses occurred in UTI caused by Proteus and Klebsiella.

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[Microscopic hematuria in children].

The AA. studied ninety children affected by microscopic hematuria whose origin was not clear. Periodic controls have been effectuated during a period from one to five years. The hematuria is spontaneously disappeared in the 46,7% of the cases. In sixteen children (17,7%) the hematuria was also present in some relatives, nine children were affected by urinary tract malformations. Only twenty subjects were affected by a significant renal pathology.

Biopsy↗

[Reye's syndrome: pathogenetic problems (author's transl)].

The authors describe six subjects with Reye's syndrome. All subjects died nevertheless the treatment (exchange-transfusions infusions of citrulline and ornithine). The autoptical studies showed cerebral oedema and fatty degeneration of the liver. Hepatic and seric OTC activity was measured in three patients: enzyme activity was virtually absent in one patient and normal in the other two. Instead in one patient was found partial CPS deficiency. However, Reye's syndrome is not only correlated with enzymatic deficiency of urea's cycle but sometimes also with toxic and metabolic causes.

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