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V A Gerasin

Publications and source records attributed to V A Gerasin.

At least 37 records · Page 2Linked to original sources
PubMed1983

[Current bronchological methods of diagnosis of lung cancer].

On the basis of an analysis of results of studying 541 patients with lung cancer the authors consider that bronchoscopy can diagnose the central lung cancer practically in all the patients including the early stages of the disease before the development of changes in the lungs on roentgenograms. The histological verification of the peripheral lung cancer of the root and median zones is ensured in 77% of patients by bronchofibroscopy under local anesthesia with the transbronchial peripheral forcepts and brush biopsy under the roentgen and TV control. Bronchological diagnosis of cancer of the subpleural zone still remains less effective.

Adult↗
PubMed1979

[Epithelial permeability study of the bronchi in chronic bronchitis using an electron-dense tag].

An electron dense tracer, horseradish peroxidase (HRP), treated with DAB-H2O2 for electron histochemical demonstration of peroxidase was used in an effort to find out whether or not the human bronchial epithelium was permeable to some macromolecules in chronic bronchitis. The biopsy specimens obtained from 5 patients at bronchoscopy and cultured in a medium with 2% HRP for 1-6 hours showed the reaction product to be distributed within intracellular spaces of the epithelium as well as in some vesicles and vacuoles of the apical portion of the ciliated cells. When 2% HRP solution was topically applied on the bronchial epithelium surface of a narcotized patient for 10 min followed by biopsy of this part of the epithelium fixation and treatment for HRP demonstration, electron dense precipitates were identified only within some intercellular spaces. It is suggested that some intercellular contacts of the bronchial epithelium in chronic bronchitis are permeable to macromolecules, and that the ciliated cells of the bronchial epithelium are capable of endocytosing some macromolecules from the surface of the mucosa.

Adult↗