Biomedical subjects
Publications and source records attributed to V B Simonenko.
160 patients with stable stress angina pectoris (SSAP) received combined treatment. One of the modalities was information-wave impact generated by devices Azor-IR, Chrono-DMW (microwaves), Chrono-EHF. The impact from Azor-IR proved most effective as it reduced the amount of medication without loss of therapeutic activity.
The paper presents the algorithm for diagnostic search for sick sinus syndrome on the basis of clinical and functional data obtained at ECG, Holter ECG monitoring, electrophysiological examination; it also outlines indications for conservative and surgical treatment.
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Adaptation of patients with gastroduodenal ulcer (GDU) to intermittent normobaric hypoxia is effective in the treatment of this disease. Some GDU patients have functional pulmonary hypertension. Single procedure and a course of normobaric hypoxic therapy have no negative effect on pulmonary hemodynamics. Overloading of the right heart in GDU patients does not contraindicate a course of breathing gas hypoxic mixture created by Strelkov's apparatus.
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Leningrad (blockade) hypertension observed in survivors of the Leningrad blockade during the World War II is a unique form of hypertension initiated and maintained pathogenetically by disturbed neuroregulation resultant from a severe psychoemotional stress. Pathogenesis of Leningrad hypertension involves mechanisms playing a key role in pathogenesis of other forms of essential hypertension. A characteristic feature of this pathogenesis is interaction of the initial and key neurogenic factor with such hypertensive factors of alimentary-dystrophic genesis as lesions of the vascular wall secondary to marked hypoproteinemia and hypovolemia. Later, in addition to hypertension the patients developed atherosclerosis, nephrosclerosis and other diseases.
Intravenous laser therapy in combination with medication was conducted in 41 elderly patients with coronary heart disease (633 nm, 1 mW, 124 mW/cm2). The study of qualitative and quantitative (osmotic resistance) erythrocyte indices of blood demonstrated the change of erythrocyte number in circulating blood by the third laser procedure. Frequency of these changes correlated with duration of the treatment course. Intravenous laser therapy had a wider spectrum of effects on erythrocyte number than medication. Changes in erythrocyte number in the peripheral blood upon intravenous laser radiation reflects efficiency of treatment of coronary heart disease patients.
Complex examination of myocardial contractility (MC) including modified (vertical) ballistocardiography (MBCG) covered 109 patients with coronary atherosclerosis. The MBCG registers early MC defects typical for patients with coronary atherosclerosis, ischemic heart disease. It is highly sensitive. Algorithms for diagnosis of the above defects have been developed. MBCG can be widely used in practical cardiology as a highly informative method for MC evaluation.
Medical histories of 167 patients with tumors of chromaffin tissue were analyzed. Pheochromocytoma was diagnosed in 124 (74.2%) patients, pheochromoblastoma--in 32 (19.2%), extraadrenal tumor--in 11 (6.6%): paravertebral (4), between aorta and vena cava inferior (2), behind the tail of the pancreas (1), at lower pole of the kidney (2), in Zukerkandl's organ (1), in the urinary bladder (1). Complex examination (hormonal profile, US, CT, MRT) was carried out in all the patients, in difficult cases in 71 (42.5%) patients angiography was performed, and in 7 (4.2%)--scintigraphy. The device examination provided accurate diagnosis in all the cases. In the majority of patients (72) clinical picture of the disease was characterized by a typical crisis course. There were no clinical symptoms in patients with "silent" pheochromocytoma, tumor was revealed occasionally in all the cases. One hundred and sixty-four patients were operated. Total lethality was 3.6%. Long-term results were analyzed in 137 patients. Radical removal of pheochromocytoma led to stable normalization of arterial pressure in 73.2% patients. Non-invasive methods (polyposition US with colored doppler, CT, MRT) are methods of choice for topic diagnosis of pheochromocytoma. Sensitivity of US with colored doppler reached 94.3%.
A comparative ultrasound and radiological investigation of gallbladder and hepatic tree function was made in patients after operation with creation of artificial stomach, Billroth I and Roux operations. The control group consisted of 30 unoperated patients. Scintigraphy discovered gallbladder dyskinesia in 12 (18.7%) patients of the study group and in 6 (20%) controls. Ultrasonography--in 15 (33.3%) patients of the study group, 5 (25%) patients after distal resection of the stomach with pyloriform gastroduodenoanastomosis, 18 (51.47%) patients operated by Roux and 5 (16.6%) controls, respectively. It is shown that normal transduodenal passage of food has a positive effect on gallbladder and liver functions.
The authors' studies demonstrate that 87.5% of patients with exacerbation of moderate bronchial asthma have cardiac arrhythmias most of which have favorable prognosis. Most of the arrhythmias were supraventricular. Hypercatecholaminemia is considered one of the mechanisms contributing to development of arrhythmia in bronchial asthma exacerbation. Administration of diltiazem proved that this drug is highly effective in the treatment of both supraventricular and ventricular arrhythmias in asthma patients.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.