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Biomedical subjects

V B Simonenko

Publications and source records attributed to V B Simonenko.

At least 37 records · Page 2Linked to original sources

[The prevention of stroke: the traditions and the outlook].

The article deals with the clinicians' views on the widely used methods of brain circulation disorders prevention. On their own experience and on the literature data the authors make a conclusion, that insult is being caused by a number of etiological and pathogenic factors. They discuss some methods of hemodynamics reserve estimation and formulate new ideas for the disorders' possible development.

Cerebrovascular Circulation↗

[Carcinoid tumors].

Carcinoid tumors are new growths from neuroendocrine cells. The following clinical variants of carcinoid were observed in 11 patients with histologically verified carcinoid: 1) asymptomatic variant (an occasional finding at endoscopy)--2 cases; 2) carcinoid with symptoms of a mass detected at surgery--2 cases of intestinal ileus, 2 cases of appendix carcinoid simulating acute appendicitis; 3) carcinoid with hepatic metastases and carcinoid syndrome with unknown primary focus--2 cases; 4) carcinoid with metastases to the liver and carcinoid syndrome with location of the primary tumor in the lungs (2 cases) and pancreas (1 case). It is stated that carcinoid tumors are encountered more frequently than diagnosed (0.1-0.5% of all the tumors). Manifestations of carcinoid syndrome allow to diagnose carcinoid only at late stage when a large mass of hormone-active tumor tissue and metastases to the liver are present.

Appendiceal Neoplasms↗

[Prevention of ischemic stroke and conception of hemodynamic reserve].

Central and cerebral hemodynamics was studied using echocardiography and transcranial dopplerography in 200 poststroke patients over 60 in the course of 5-year follow-up. It was established that cardiac hypodynamic syndrome, i.e. continuous or paroxysmal fall of minute blood volume below 3 l, is the most significant contributing factor in the onset of cerebral ischemia. Drugs are recommended for prevention of ischemic stroke. Those lowering cardiac hemodynamic reserve should be excluded in patients at high risk of acute failure of cerebral circulation.

Angioplasty↗

[Various combinations of antihypertensive drugs: comparative assessment in elderly patients].

68 elderly patients with hypertension stage II were treated with different combinations of antihypertensive drugs. 36 patients of group 1 received inhibitors of angiotension-converting enzyme (captopril) and calcium antagonists of prolonged action (adalat CL). 32 patients of group 2 received captopril and beta-blockers (atenolol). The patients were followed up for 12 months. Before and after the treatment the patients underwent 24-h monitoring of arterial pressure and echocardiography. The antihypertensive effect was more pronounced in group 1. Both combinations of the antihypertensive drugs prevented development and progression of myocardial hypertrophy due to hypertension. No significant changes in left ventricular contractility in response to these drug combinations were found.

Aged↗