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V Basaca-Sevilla

Publications and source records attributed to V Basaca-Sevilla.

At least 19 recordsLinked to original sources

HIV-1 seropositive women in the Philippines: pregnancy outcome and perinatal transmission of HIV-1.

Annual surveillance studies were initiated in 1985 to determine the incidence and prevalence of HIV-1 infection in female prostitutes registered through the Social Hygiene Clinic System of the Philippine Department of Health. All of the confirmed HIV-1 seropositive women detected in the above surveys who could be contacted were followed up about every three months to monitor their clinical and immunological status. Since we regularly interviewed and examined these HIV-1 seropositive women, we were able to note the occurrence of pregnancies following HIV diagnosis. By September 1990, 54 HIV-1 seropositive women (aged 18-35) detected from the above surveys had been interviewed and examined. Twenty-six of these HIV-1 positive women had a total of 37 pregnancies. Eight were pregnant at the time of HIV diagnosis: three term deliveries, one premature delivery (PD) at eight months, three abortions, and one lost to follow-up while still pregnant. Five of these eight had repeat pregnancies: two term deliveries, two abortions, and one lost to follow-up while pregnant. Eighteen other women became pregnant one or more times after HIV diagnosis: seven term deliveries, 13 abortions, two PDs, one ectopic pregnancy terminated, one currently pregnant, and one lost to follow-up during pregnancy. There was no clear indication from clinical examinations and CD4+ cell counts that pregnancy exacerbated the course of HIV-1 related disease in these women. One of the 12 term infants has died and eight have developed non-specific findings that are suggestive but not diagnostic of HIV infection.2+ strongly seropositive by both ELISA and Western blot assay at 16 months.

Adult↗

Capillariasis philippinensis: a fish-borne parasitic zoonosis.

Fish from lagoons in Northern Luzon, Philippines, have been shown experimentally to be intermediate hosts of Capillaria philippinensis. Eggs ingested by the fish hatch in the intestines and the larvae double in size in 3 weeks. When fed to monkeys, Mongolian gerbils and birds, the larvae develop into adults and reproduce. Fish from the lagoons or purchased from the market were fed to gerbils and the animals developed patent infections, demonstrating natural transmission of the parasite. Philippine and Thailand populations have the habit of eating uncooked freshwater and brackish water fish and some have been experimentally infected with C. philippinensis. These countries report the largest number of cases of intestinal capillariasis. Fish-eating birds are now considered natural hosts for the parasite, fish the intermediate hosts, and humans accidentally become infected by eating infected fish.

Animals↗

Sexual behavior of Filipino female prostitutes after diagnosis of HIV infection.

A study of female prostitutes in Manila who tested positive for human immunodeficiency virus (HIV) antibody ascertained demographic and sexual behavior information following diagnosis. Counselling alone did not appear to have a major impact on the sexual behavior of the HIV positive women since most continued to work as prostitutes. Switching from high risk to low risk jobs in bars is not effective in preventing HIV positive women from engaging in prostitution. Revoking work permits is only effective if enforced with adequate follow up. Alternative job training programs may offer a viable approach.

Contraceptive Devices, Male↗

Epidemiology of HIV infection among prostitutes in the Philippines.

Between 1985 and 1987, examinations for human immune deficiency virus (HIV) antibody were done on 25,392 prostitutes working in 64 cities throughout the Philippines. The country-wide seropositivity rate among prostitutes based on this sample was 0.8/1,000. Of the HIV cases, 85% were working in just two cities whose prostitute populations comprised 50% of the total sample. The average incidence rate for the same two cities after 1 year was 2.3/1,000. HIV antibody-positive women were enrolled in a case-control study to determine demographic and epidemiologic risk factors. This study involving 34 HIV-positive prostitutes and 61 randomly selected negative control prostitutes did not reveal any risk factors related to sexual or other types of behavior. A history of genital warts, a history of abnormal vaginal discharge, and cytomegalovirus antibody were significantly more frequent in the HIV-positive cases than in the controls; however, by logistic regression analysis, only an abnormal vaginal discharge was independently associated with HIV infection. Absence of any evidence of transmission by blood transfusion or i.v. drug abuse suggests that HIV was introduced by the heterosexual route.

Adult↗

Albendazole in the treatment of intestinal capillariasis.

Albendazole or Zentel a benzimidazole derivative, was used to treat intestinal capillariasis in hospitalized patients seen in Northern Luzon in the Philippines. In initial studies, four patients responded satisfactorily to the drug in dosages of 400 mg/day in divided doses for 20 days. This is the same dosage used for mebendazole, which has been the drug of choice in treating the parasitosis. In further studies, 16 patients with Capillaria philippinensis, were treated with 400 mg/day of the drug for 10 days, and 15 were completely cured. The one treatment failure was found to be passing eggs of the parasite three months later, and was retreated with the standard mebendazole regimen of 400 mg/day for 20 days. Side effects attributed to albendazole were not reported in any of the patients. Albendazole, 400 mg/day in two divided doses, is now the recommended drug of choice in Northern Luzon in the Philippines.

Adolescent↗

HBsAG and HBeAG markers among pregnant women in Manila, Philippines.

The sera of 5,684 pregnant women were tested for HBsAG and 432 (7.6%) were found positive. Positive HBsAG sera were then tested for the e antigen and of 413 tested, 115 or 27.8% were positive. The over-all prevalence rate of e antigen was 2.03%. All women were asymptomatic. Six of 13 HBsAG-HBeAg-positive mothers delivered infants who became HBsAg-positive within two years of age for a rate of 46%. The findings support earlier studies on the importance of the e antigen as an index of perinatal transmission. Also, they support evidence of unusually high rates of transmission among Asian ethnic groups.

Adolescent↗

Studies on Echinostoma ilocanum in the Philippines.

Echinostoma ilocanum is widespread among the Philippine Islands but only 3% of over 30,000 stools were found to be positive for eggs. The prevalence rates were highest in Ilocana populations of northern Luzon; 11% of over 7,000 stools examined, however, rates as high as 44% were found. Pila luzonica is eaten uncooked by some people and metacercariae from these snails developed into adults in a number of laboratory animals. Rats, mice and hamsters were the most susceptible with patent infections developing as early as 7 days and lasting for 328 days. There seems to be little disease in humans and animals infected with this parasite.

Adolescent↗

Prevalence of Trichomonas vaginalis in some Filipino women.

Vaginal specimens obtained from 1,284 hospitality girls and 87 expectant mothers were examined for Trichomonas vaginalis by first examining material collected from vaginal swabs and after incubation in Feinberg and Whittington culture medium. Twenty-four percent of the specimens examined, shortly after the cotton-tip swab was placed into 1 ml culture medium, were positive by direct microscopic examination and 37% positive following 3 to 5 days incubation at 37 degrees C. Only 3 of the specimens from mothers were positive after the first examination and 4 positive after culture. These high prevalence rates are expected among hospitality girls and are the highest rates thus far reported from the Philippines. These results provide convincing evidence of the value of using cultural methods in determining prevalence rates for Trichomonas vaginalis infections in females.

Female↗

Leptospirosis in the Philippines.

Leptospirosis was first isolated in the Philippines from one of the human cases of Weil's Disease in 1932 and from then up to 1970 a total of 65 cases were studied sporadically. From 1971 up to 1973 a total of 390 cases were studied out of which 82 (21.02%) were found positive by isolation and serological examination. An outbreak of leptospirosis was followed up from 1976 to 1983 in a penal farm in Sablayan, Mindoro. At the time of the outbreak, 31% of the sera from patients and those with complaints reacted to one or more antigen pools with 40% of these reactors reacting to only one antigen pool. Only one percent of prisoners and residents without complaints reacted to one or more antigen pools, with 80% of these reactors reacting to pool 3 alone. Three and half years later, a first follow-up was done in which 9.07% reacted to one or more pools. Of these, 42% reacted to pool 2 and 82% to pool 3 alone or in combination with other pool. Ninety five percent of those reacting to Pool 2 reacted to L. pyrogenes and 88% of those that reacted to Pool 3 reacted to L. autumnalis. More than three years later after the first follow-up, a second follow up was done. This time 2.29% reacted to one or more pools. Most reacted specifically to L. autumnalis. The residents outside the penal farm were all non-reactive. Sampling from another penal colony and in four agricultural areas revealed no significant reactivity.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗

Attempts to modify treatment of intestinal capillariasis.

Attempts to reduce the standard treatment of intestinal capillariasis of 200 mg mebendazole twice daily for 20 days were not successful. Two of 13 patients given mebendazole at single daily dosages of 500 mg per day for 16 days relapsed 3 to 6 months after treatment. Attempts to reduce the treatment to 14 days were even less satisfactory in that 4 of 8 patients treated experienced relapses 2 to 9 months later. Since intestinal capillariasis can be fatal it is recommended to continue the use of the standard schedule of 400 mg mebendazole daily for 20 days for new cases and 30 days for relapsed cases until a more effective drug is available.

Animals↗

Experimental transmission of Capillaria philippinensis to birds.

Capillaria philippinensis larvae from fish and adult and larval forms of the parasite from gerbil intestines established parent infections when given a stomach tube to several species of birds from Taiwan. Adult males, oviparous and larviparous females and larval stages were found in Nycticorax nycticorax, Bubulcus ibis, Ixobrychus sinensis, Gallinula chloropus and Amaurornis phoenicurus. C. philippinensis also developed in pigeons, Rostratula benghalensis, a few Anas spp. and chickens. Some birds died of the infection while others recovered; most could not be re-infected after repeated exposure. Autoinfection also occurred in most birds. Eggs from an egret hatched and the larvae developed in fish intestines. This is the first group of animals indigenous to the endemic area that could be infected with C. philippinensis and although no naturally infected birds have been found in the area, fish-eating birds should be suspected as potential reservoir hosts. A fish-bird life-cycle is thought to be occurring throughout Asia but intestinal capillariasis is reported only in areas where the human population eats raw freshwater fish.

Animals↗

Additional isolations of Japanese encephalitis virus from the Philippines.

Japanese encephalitis virus was isolated from Culex tritaeniorhynchus, Culex bitaenorhynchus and Anopheles annularis mosquitoes collected from San Jose, Nueva Ecija, South Central Luzon in the Philippines. This is the second report of the isolation of the virus from mosquitoes in the Philippine Islands.

Animals↗