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Biomedical subjects

V Becker

Publications and source records attributed to V Becker.

At least 109 records · Page 6Linked to original sources
PubMed1975

[Minimal cardiac transit time in thyroid disorders and in the effort syndrome].

Minimal transit times (MTTs) were determined with the Fucks-Knipping gamma camera from differences between arrival times in consecutive cardiac compartments of blood radioactively labelled with 113m-In-DTPA Measurements were made on 50 patients with effort syndrome, 59 patients with hyperthyroidism before and after thyroid suppression therapy partly suffering from associated heart disease, and 25 patients with hypothyroidism before and after therapy with thyroid hormone. In patients with effort syndrome and hyperthyroidism, MTTs were often, but not always shortened below the control values; consequently, in case of associated heart disease, MTT-prolongation may be masked in such instances where hyperthyroidism causes MTT shortening. Hypothyroidism caused MTTs to be prolonged. The prolonged MTTs reverted to normal values upon adequate therapy with thyroid hormone.

Adult↗
PubMed1975

[Carcinoma of the pancreas: pathologic anatomy (author's transl)].

Carcinoma of the pancreas is seen in 1.2 percent of autopsies. Often it is not possible to determine definitely: whether it is a carcinoma of the head of the pancreas, of the papilla, or of the distal part of the common bile duct (periampullary carcinoma). 90 percent of these carcinomas arise in the small ducts. They cannot be recognized by ERCP until spreading into the main duct has occurred. Differential diagnosis is concerned mainly with differentiating between chronic pancreatitis and carcinoma of the pancreas. Chronic pancreatitis and carcinoma of pancreas are not mutually exclusive; on the contrary they are closely related in diagnosis and pathogenesis. There can be no carcinoma of the pancreas without pancreatitis. For an accurate diagnosis which is vital, a diagnostic laparotomy should be performed at an early stage.

Adult↗
PubMed1975

Attempts to detect virus-specific DNA sequences in human tumors. III. Epstein-Barr viral DNA in non-lymphoid nasopharyngeal carcinoma cells.

Fourteen tumors of the nasopharyngeal region were analyzed for the presence of Epstein-Barr virus-specific DNA by DNA-cRNA hybridization. These data were compared to the histology of the respective tumors and the seroreactivity of the tumor-bearing patient against EBV-related antigens. With one exception, all tumor pieces containing nasopharyngeal carcinoma cells hybridized significantly with EBV-cRNA. Tumors of predominantly epithelial morphology annealed in the highest range. In situ-hybridization of freeze sections from a tumor containing almost equal amounts of tumor cells and lymphocytes revealed hybridizing DNA within nuclei of non-lymphoid cells. Although these data do not exclude the presence of EBV-DNA within lymphoid cells, they clearly demonstrate that in nasopharyngeal carcinomas the vast majority of EBV-specific DNA rests within non-lymphoid cells.

Carcinoma↗