Craniofacial custom implants following oncologic surgery of anterior skull base tumors.
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Adenocarcinoma↗
Biomedical subjects
V Cervelli
Publications and source records attributed to V Cervelli.
[Surgical lesions of the facial nerve: anatomy, semiology and nervous function].
The extracranial part of the facial nerve is a frequent seat of lesions, which can be either congenital, or traumatic, or surgical, or neoplastic. The authors review the semeiology of the lesion and discuss the techniques for the preservation of facial nerve function.
Facial Nerve↗
Extracorporeal blood recirculation and beta-2-microglobulin plasma levels during hemodialysis.
Beta-2-microglobulin (beta 2m) plasma levels during hemodialysis have recently been considered markers of membrane biocompatibility. The aim of this study was to assess if generation of beta 2m from blood cells in contact with the membrane could account for changes in beta 2m plasma concentration during hemodialysis. The role of heparin was studied as well by comparing conventional with heparin-free dialysis. beta 2m plasma levels were measured in six patients during 12 Cuprophan (Cu) and 12 Eval (E) non-consecutive hemodialysis sessions without ultrafiltration. E membranes were compared with and without heparin. beta 2m plasma levels significantly increased with Cu but not with E. A total of 200 ml of blood from four other patients was recirculated ex vivo before Cu hemodialysis in Cu or E and then reinfused into the patient. A drop in beta 2m concentration was observed in the recirculating blood, recovery of beta 2m from the washed filter was higher with E, and reinfusion of recirculated blood to the patient was not associated with significant increases in beta 2m plasma levels. Hemodialysis with a new Cu filter, following reinfusion, did not produce significant increase in plasma beta 2m concentration. In conclusion, 1) beta 2m plasma levels change during Cu, but are not associated with hemoconcentration from ultrafiltration nor with local release from the blood leaving the filter, 2) beta 2m binding to the membrane may account for decreased levels in recirculated blood, 3) E membranes both with and without heparin do not increase beta 2m plasma levels and reinfusion of recirculated blood blunts the beta 2m changes observed with Cu.
Aged↗
Immediate TRAM flap breast reconstruction in an obese patient with relapsing benign phyllodes tumor: report of a case.
The authors present a case of relapsing benign phyllodes cystosarcoma of the breast in an obese female treated with a simple mastectomy and an immediate reconstruction using a bipedicled transverse rectus abdominis musculocutaneous (TRAM) flap. After a brief review of treatment options for phyllodes tumors, they discuss the advantages of TRAM flap breast reconstruction, suggesting that it may also be applied in obese patients.
Breast Neoplasms↗
Titanium bone-integrated implants in extraoral facial prosthetic rehabilitation: surgical planning and long-term follow-up.
The authors report on their clinical experience in the reconstruction of complex facial deformities using titanium osseo-integrated implants for the retention of soft silicone prostheses. They also evaluate the importance of this surgical technique as a viable alternative to traditional reconstructive procedures using autologous grafts, both in patients with severe osteomuscular defects and corrective surgery of unsuccessful reconstruction operations. The patients who underwent implantation operations were studied by CT 3D and 99m Tc SPECT (Single Photon Emission Computerized Tomography) procedures to evaluate osseo-integration at 3 weeks, 3, 6, 12, 24 months. The study demonstrates that the radiation emission peaks three weeks after surgery with the maximum bone remodeling activity, and after the functional loading of the implants, 3 months after surgery. High uptake past the eight month after surgery has never been detected and must be considered abnormal. SPECT offers the possibility of obtaining a three dimensional reconstruction of the photon emission of selected structures. The use of these nuclear medicine methods in addition to traditional-type radiological procedures introduce new possibilities, although still in the clinical experimentation phase, for the long-term follow-up of the inserted implants in craniofacial rehabilitation.
Adult↗