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Biomedical subjects

V Hegedüs

Publications and source records attributed to V Hegedüs.

At least 55 records · Page 3Linked to original sources

Kidney distension during IV urography in normal rats and in rats with artificial unilateral renal artery stenosis.

Acute changes in kidney size during IV urography were studied in normal rats and in rats with artificial unilateral renal artery stenosis. In normal rats, IV bolus injection of sodium iothalamate (400 mg I/ml), 1.5 ml/kg body weight, produced an increase in area of the renal silhouette by an average maximum of 12.7% after 60 seconds. In nine out of ten rats which developed hypertension after left sided renal artery clamping, renal distension was either small or absent on the stenosed side, while the contralateral right kidney showed normal distension during IV urography. Two out of three rats, which remained normotensive after renal arterial clamping, showed normal distension of both kidneys. These results confirm earlier observations in man that the acute changes in size of the kidney during IV urography can be used as an aid in the urographic screening of hypertensive patients for significant renal arterial stenosis. In all rats with arterial clamp and hypertension, the stenosed kidney was smaller than its contralateral mate. An index between the size of the non-stenosed and the stenosed kidneys greater than 1.15 was only seen in these particular rats.

Animals↗

Relief of pancreatic pain by radiography-guided block.

A 7-year experience with radiography-guided blockade of the celiac ganglia in patients suffering from pancreatic pain is described; 36 patients had carcinoma of the pancreas and nine had chronic pancreatitis. The importance of fluoroscopic guidance of deposition of the blocking agent is stressed. The success rate of this procedure is similar to operative intervention for interruption of the pathways of pain conduction. Radiography-guided celiac ganglion block along with enzymatic substitution for increasing pancreatic insufficiency are recommended for effective palliative treatment.

Autonomic Nerve Block↗

Volume changes in the rat renal cortex during urography.

At different periods of urography rat kidney were instantly frozen at -165 degrees C. Using appropriate histological techniques and planimetry of different cortical compartments and fractions the structural background of renal cortical volume variations during urography was elucidated. The renal cortex reacted to intravenous injection of hypertonic contrast medium with an immediate increase of volume, followed by a decrease from 30 to 60 seconds. Measuring the volume shares of different cortical compartments, the complex nature of cortical volume variations during the first minutes of urography could be demonstrated. Subdivision of the tubular compartments into cellular and luminal fractions showed even greater complexity of volume variations. All the major cortical volume changes came to an end approximately three minutes after the injections.

Animals↗

Interstitial handling of aminoglycoside antibiotics and radiographic contrast media in the kidney.

Lymphatics of the mammalian kidney originate in the loose connective tissue around large blood vessels. This paravasal tissue drains the interstitum. The intarenal lymphatic system consists of interlobular, arcuate, and interlobar vessels according to the architecture of the arterial system. The interlobar vessels drain into the hilar lymph vessels. Capsular lymphatics are connected with the interlobular lymphatics inconsistantly. The renal medulla is drained by the venous vasa recta exclusively--there are no lymphaties in the medulla. Lymphatic fluid is mainly formed along the small renal veins as vascular transudate. After i.v. bolus injection concentrations of aminoglycosidic antibiotics in renal lymph reflect plasma values closely. Radiographic contrast media in renal lymph also showed a close correlation with plasma values with some indication of tubular secretion.

Aminoglycosides↗

Double contrast examination of the stomach. An improved technique.

Double contrast examination of the stomach has a greater accuracy than conventional barium meal, especially in the diagnosis of minor gastric lesions. The use of a common drinking straw with a side-hole to introduce air simultaneously with the barium suspension after gastric emptying with metoclopramide and using short acting hypotonic agents like Buscopan and Glucagon provides a practical and effective simplified technique for double contrast examination of the oesophagus, stomach and duodenum.

Adolescent↗

Ultrasound-guided drainage of fluid-containing masses using angiographic catheterization techniques.

A new method combining experience of ultrasonic diagnostic and puncture technique with the use of existing angiographic tools is described. Using this method, intraabdominal fluid-containing mass lesions were drained for diagnostic and therapeutic purposes. In three patients, severe life-threatening lesions were successfully diagnosed and treated solely by this method. In one other case the method greatly facilitated major surgery. The importance of integration of diagnostic radiology and ultrasound is stressed.

Abscess↗

Pelvimetry in breech and cephalic presentation.

Pelvic measurements in a group of 115 women delivering in breech presentation were compared with those in a group of 100 delivering in cephalic presentation. The average pelvic measurements were all a few mm larger in the breech cases and the average sum of the outlet diameters was significantly larger. Pelvic disproportion was not more common in breech presentation and no support was found for the theory that large pelvic measurements predispose to breech presentation. The small differences found are attributed to the moulding of the pelvis occurring during parturition.

Breech Presentation↗