PubMed Health⌕ Search

Biomedical subjects

V I Khrupkin

Publications and source records attributed to V I Khrupkin.

At least 19 recordsLinked to original sources
PubMed2004

[Current principles of correction of leg shapes in reconstructive and aesthetic surgery].

Main principles which should be followed when choosing the strategy of treatment in patients with deformities of lower extremities are describes. The authors' experience includes 213 patients with deformities of lower extremities, 59 of them were operated upon. Basing on this experience the authors have developed a classification allowing systematization of the methods for correction of deformities of legs. The following factors were taken into account: the character and degree of the deformity, the degree of impairment of the joint functions, compensatory changes, the degree of alteration of soft tissues, patient's age and the esthetic effect estimated by the patient.

Humans↗
PubMed2004

[Syndrome of enteric insufficiency in patients with diffuse peritonitis: evaluation of the severity and outcome of the process].

The authors have developed a method of assessment of the degree of the enteral insufficiency syndrome (EIS). The method was used in 2006 peritonitis patients on the basis of 42 clinical-laboratory indices expressed by 10 score scale. A formula for establishing the coefficient of EIS is proposed in cases of the absence of all the indices, the average intervals of its possible degrees are shown. An express formula was developed for the calculation of the prognostic coefficient and its degree intervals. Randomization in the approaches to diagnosis and treatment allowed lethality to be reduced from 26.9% to 12.9%, the frequency of complications--from 12.7% to 7.2%.

Algorithms↗
PubMed2004

[Modern ideas concerning the mechanisms of gunshot injury formation (Communication 1)].

The affect of gunshot small arms depends on the weight, speed and moment of projectile's inertia, which determine the trajectory of its movement in the object's substance and the degree of braking characterizing the fullness of energy transmission. The experimental investigations on animals show that the mechanism of tissue lesion during the gunshot injuries has a very complex character and includes both the projectile's direct effect and initiation of some physical phenomena leading to significant tissue damage distally from the wound canal.

Firearms↗
PubMed2004

[Modern ideas about the mechanisms of gunshot injury formation (Report 2)].

The results of experimental study of circulatory acute phase response to the gunshot trauma have shown that triggering of pathologic cascade defined as the traumatic shock is attributed to the free radical concentration created by the wounding projectile in the damaged tissues due to injury sphere formation. So the further study of etiology and pathogenesis of combat pathology is required, the results of which will permit to improve considerably the quality of medical aid rendered to the wounded and casualties.

Abdominal Injuries↗
PubMed2003

[Minimally-invasive combined radiosurgical interventions in diagnosis and treatment of pulmonary artery thromboembolism].

Basing on the analysis of results obtained during the investigation and treatment of 38 patients suspected of pulmonary artery thromboembolism (PAT) the algorithm of measures applied in our hospital was developed. Its purpose was to put the PAT diagnosis and treatment in order. In our investigations the leading treatment method was the regional infusion therapy conducted through the transformation of diagnostic catheterization of pulmonary artery trunk into the treatment intervention. With the purpose of embolus hydrodynamic destruction the regional thrombolysis was conducted under conditions of fast high-pressure perfusion. It was preceded by the mechanical recanalization of thrombosis zone by the distal part of probe in order to create more favorable perfusion conditions. To prevent the repeated PAT when the source of thromboembolism was revealed the cava-filter implantation in the infra-renal part of inferior cava was performed.

Combined Modality Therapy↗
PubMed2003

[Enteral therapy of the syndrome of intestinal insufficiency in patients with peritonitis].

Sixty five patients with peritonitis were examined and divided into two groups. The operative intervention in all the patients included transnasal intubation of the small intestine. The basic enteral therapy used in the first group of patients was made with the glucose-saline solution and transition to a balanced polysubstrate mixture "nutrient standard" with the increasing concentration. For the patients of the second group a special program was developed for enteral therapy in which glutamine and pectine were included in the glucose-saline solution as well as nutrient mixtures containing middle chain triglycerides. Active decompression of the small intestine followed by the enteral administration of the nutrient mixtures facilitated quicker correction of the intestinal insufficiency in patients with severe forms of peritonitis.

Adult↗
PubMed2002

[Problems and prospects of post-graduate training at military-medical cadres].

The actual problems of advanced post-diploma training of RF AF medical cadres is analyzed in the article. The investigation of paramount directions of military-and-medical education reform was conducted, the data on additional military-and-medical education system were generalized. The present average annual output of all bases of additional education in RF AF system was subjected to analysis. The data on the students' training cost in the State institutions for physicians' advanced training (SIPAT) and the same civilian medical higher schools are presented. It is noted that the one student training prime cost in RF AF SIPAT is considerably lower. Present conceptions concerning the advanced system of military-and-medical cadres' training were analyzed. The main problems of RF AF SIPAT are presented; and until the problems are solved it will be impossible to optimize the training of medical service specialists. It is shown that under conditions RF AF, military- and medical reformation SIPAT can become the leading educational, scientific and medical center of post-graduated and additional professional education of military physicians.

Education, Graduate↗
PubMed2002

[Application of viable cryopreserved alloderm transplants in the treatment of wound defects of soft tissues].

An original method is proposed for treatment of long-standing intractable wounds and trophic ulcers using viable cryopreserved allodermotransplants and a distant air-plasma treatment. The main source of the allodermotransplants is the cadaverous skin. It was shown that the cadaverous skin taken during 17 hours after the donor's death was viable. The maximum period for storage of the viable skin when the worked out preservative is used at the temperature regimen -18 degrees C is 10 days, and at -70 degrees C it can be as long as 45 days. The analysis performed included 101 patients with long-standing intractable wounds and trophic ulcers. In 51 of them the new worked out method was used. An analysis of clinical and histomorphological data has proved that the application of the viable cryopreserved allodermotransplants and distant air-plasma treatment favor the better course of reparative processes. By the end of the forth week the wounds were completely closed in 19.7% of patients, the wound areas were considerably less (more than by 50% of the initial size) in 43.1%, less reduction of the wound area (less than 50% of the initial size) in 27.4%, in 9.8% there was no effect. No negative results were noted. It should be noted that closure of the tissue defect can be achieved by stimulation of the physiological regeneration of the patient's tissues. This method of regeneration of the skin is effective in trophic ulcers, long-standing intractable wounds and is also recommended in case of deficit of donor resources or when the severe state of the patient does not allow active surgical treatment.

Cell Survival↗
PubMed2000

[Use of gas-current coagulation in the local treatment of gunshot wounds].

The article is devoted to the using of gas-current coagulation for treatment of gunshot wounds in experiment. A new technology of physical action on biological tissues allows the simultaneous performing of hemostasis, sterilization of the wound surface, dissection and evaporation of the tissue. The isolation of the wound surface from unfavorable aggressive factors of the environment due to the layer of thermal necrosis results in shortening the 1 phase of the wound process and in earlier development of its second phase. Healing proceeds by the type of productive inflammation. The use of the gas-current coagulation during the performing of the primary surgical treatment of gunshot wounds allowed to considerably reduce its time, improve its quality, substantially lessen the amount of infectious complications, considerably improve the indices of the wound process and results of treatment.

Animals↗