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Biomedical subjects

V I Khrupkin

Publications and source records attributed to V I Khrupkin.

29 records · Page 2Linked to original sources

[Use of physical plasma in surgery of wounds and wound complications].

The article is devoted to the local application of high energy plasma flows in the complex treatment of wounds and wound complications. The new technology of physical action upon the biological tissues allows performing dissections, evaporation and carrying on local hemostasis and sterilization of the wound surface simultaneously. The shortening of the first phase of the wound healing process and earlier development of the second phase are due to the "biophysical isolation" of the wound surface by the thermal necrosis layer from unfavorable effects of the external medium. The healing goes on by the type of productive inflammation. The use of plasma flows during surgical treatment of purulent wounds reduces pains during the postoperative period and considerably improves results of the treatment.

Adolescent↗

[The use of air-plasma flows in military field surgery and disaster medicine].

Plasma currents of high energy are considered to be very promising in the surgical treatment of modern pathology. The scientists of this country have constructed a portable field surgery apparatus in which a heated atmospheric air assumes a form of a high-temperature thin jet used like a surgeon's scalpel. Experiments and clinical tests proved the efficacy of this microplasmotron that can destroy and coagulate body tissue when treating it with plasma. This new method has, besides hemostatic action, some noticeable antimicrobic effect that leads to acceleration of tissue granulation and wound healing. In specialized and skilled medicare this progressive and priority method should be applied for initial surgical wound treatment, secondary hemorrhage arrests and surgical interventions when a high risk of infection spreading is involved.

Air↗

[The use of a perfluorocarbon emulsion in the local treatment of wounds complicated by a surgical infection].

The article shows effectiveness of the local application of Perftoran in complex treatment of purulent wounds of soft tissues in 50 patients. Perftoran has no necrolytic and antibacterial properties and fails to make the terms of the 1st phase of the wound process shorter. Perftoran maintains the intensified development of young cell elements at different periods of healing of the purulent wounds, decreases the propagation of microorganisms in them, lessens the wound square surface, results in earlier development of marginal epithelialization and formation of the elastic cicatrix.

Administration, Topical↗

[Experience in organizing surgical care during the combat operations in the Chechen Republic].

In the article the final analysis of organization of surgical care during the local military conflict in northern Caucasus was presented. The real possibilities of different medical units such as single medical company and medical squadron of special assignment was described. Also concrete contents of emergency specialized surgical care and its role in improvement of outcomes in patients with combined combat injuries was reflected. Mortality in this patients was decreased from 25.2 to 12.8%. The defects of surgical care were analyzed and the main ways of improvement of surgical care in local military conflict were presented. In the result of using the principle of moving the medical care closer to the wounded in the whole system of consecutive care the mortality was decreased up to 1.3%.

General Surgery↗

[Traumatic disease in wounded patients].

Results of clinico-physiological, pathobiochemical, immunological and hemocoagulative studies performed at the postshock period in 186 patients with battle wounds have shown their coincidence with data obtained in critical mechanical trauma of peace-time. A conclusion is made that critical gunshot wounds are followed by trauma disease having main regularities similar to those in a critical mechanical trauma of peace-time. One can speak only about specific features of battle injuries, but to distinguish "wound disease" as an independent clinical form is thought to be illegal.

Humans↗

[Pathogenesis and treatment of gunshot wounds of soft tissues].

Based on experimental investigations and generalization of the experience with treatment of wounds the authors pay attention to principal distinctions of the gunshot wound from other kinds of open injuries, as well as to the importance of early primary surgical treatment of the gunshot wound in prophylactics of infectious complications. Data on possible use of microwave radiation and medicamentous agents for stabilization of the wound process and restriction of spread of the secondary necrosis++ are presented.

Animals↗

[The treatment of combined gunshot and blast injuries at the medical evacuation stages].

The article summarizes the experience of medical care to 3980 wounded with gunshot and blast injuries. It was found out that a number of fatal cases in concomitant traumas (23.4% of all other types of wounds) had come to 32.4%, and a number of medical discharges for unfitness--62.7%. The basic trends for the improvement of medical aid for this category of wounded are the following: rational systematization of injured, elaboration of integral prognostic systems which could be applied for concomitant gunshot injuries, differentiated approach to the problems of surgical, reanimatological and anesthesiological procedures.

Afghanistan↗