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V I Sachkov

Publications and source records attributed to V I Sachkov.

59 records · Page 4Linked to original sources
PubMedDate not supplied

[Evaluation of the effect of a high-protein diet in combination with hormone and drug preparations on immunological homeostasis indices in rheumatism patients with a low degree of activity of the disease process].

High protein diet coupled with drugs was used for the treatment of patients with protracted and latent recurrent rheumocarditis. The mean daily doses of the drugs administered were as follows: 2 g of aspirin and 15 mg of prednisolone. With clinical improvement most patients showed a decrease in the amount of blast transformed lymphocytes in stained smears of the cultures of peripheral leukocytes incubated in the presence of cardial antigen, collagen and group C streptococcal nucleoprotein. They also manifested the diminished ability on in vitro sensitized lymphocytes to produce the leukocyte migration inhibition factor.

Adult↗
PubMedDate not supplied

[Effect of diet therapy on the immunological indices in rheumatism].

Rheumatic patients with torpid and latent course of the process were kept on a protein-rich diet (up to 140.0 g of protein). The effect of the diet on the organism was appraised by the peripheral blood lymphocytes blast-transformation reaction, as the one most comprehensively reflecting the immunological status of the individual. The patients were examined in dynamics, on admission to and at the time of discharge from the clinic. The data thus obtained suggest that the protein-rich diet tends to bring down the number of activated cells in in vitro cultures.

Antigen-Antibody Reactions↗
PubMedDate not supplied

[Parameters of polynuclear cell activity in torpid and latent recurrent rheumocarditis in the process of treatment with a high-protein diet and drug preparations].

The in vitro test of direct granulation of basophils affected by specific antigens (cardial tissue, acid-soluble fraction of collagen, streptococcal allergens) was investigated in the course of treating 41 patients (29 women and 12 men aged from 20 to 50 years) suffering from a little active rheumatic fever. The patients received a complex of therapeutic measures including high-protein diet (130-140 g protein) and drugs (1.5-2.0 g acetylsalicylic acid and 15 mg of prednisolone a day). As a result of the treatment all the patients improved and demonstrated pain relief in the heart region, reduced palpitation, abatement of general weakness and fatigue. At the same time there was a decrease in the reactivity of basophilic leukocytes, shown by less number of degranulated cells in vitro, activated with specific antigens.

Adult↗
PubMedDate not supplied

[Prognostic potential of sensometry in scheduled patients during the use of drugs for neuroleptanalgesia].

Tactile and pain thresholds were determined in 116 patients 24 hours before surgery upon premedication and administration of fentanyl and droperidol during induction to anesthesia. Statistical correlation analysis has shown that high pain thresholds in patients 24 hours before surgery indicate low consumption of barbiturates during induction to anesthesia, high efficacy of drugs used for NLA, and infrequent reactions to intubation irrespective of the efficacy of premedication. Low pain thresholds after premedication predict low efficacy of drugs for NLA and high consumption of fentanyl during surgery.

Female↗