[Deceleration of chemically induced genetic mutations in mutant his strains of Salmonella typhimurium].
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Biomedical subjects
Publications and source records attributed to V Luca.
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A left ovarian gynandroblastoma in a 24-year-old woman was clinically manifest by prolonged (7 years) amenorrheas interrupted by metrorrhagies, with moderate hypertrichosis is presented. An important urinary elimination of estrogens (1.500 gamma/24 h) and of 17-ketosteroids (25 gamma/24 h) with normal 17-OH and gonadotrophins were evidenced. The microscopic examination of the operated tumor showed structures of a granulous tumor intermingled with arrhenoblastomatous structures. Restoration of the patient's sexual biological conditions.
Endometria from women with primary and secondary sterility were morphologically, optically and ultrastructurally studied; such endometria were selected by clinical and paraclinical methods. In dysfunctional endometria the most important modification consists in the perturbation of the cyclical maturation process of the epitheliostromal components, perturbation which may take place "synergically" or it may be "dissociated", in disagreement with the theoretic day of the menstrual cycle. Such perturbations took place in varied circumstances: "out of phase", luteal deficit associated with hyper- or hypoestrogenemia, or pure luteal deficit, receptivity disorders, association with specific or unspecific inflammatory lesions, anovulatory cycle. Endometrium biopsy constitutes the best method for the diagnosis of endometrial dysfunctions, showing both the ovary's global hormonal function, and the qualities of the endometrial receptor, with the corrective of the corresponding technical processes and the compulsory knowledge of some clinical data.
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