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Biomedical subjects

V M Boev

Publications and source records attributed to V M Boev.

At least 19 recordsLinked to original sources

Immune and interferon status in schoolchildren living in cities with different anthropogenic load.

Examinations of 6-11-year healthy children living in industrial cities of the Orenburg region revealed a close relationship between ecological status of the territory and some immunity parameters such as immune deficiency, interferon content, and formation of postvaccinal immunity with live measles vaccine. The most pronounced changes in the immune status and decreased postvaccinal immunity were found in a city with the greatest anthropogenic load. Changes in interferon status were similar in all cities: a 2-fold increase of serum interferon and suppressed production of interferon-alpha and interferon-gamma.

Air Pollutants↗

[Effect of the antioxidant ionol on the formation and retention of a defensive conditioned reflex during maximum physical exertion].

Administration of the synthetic antioxidant ionol to male Wistar rats prevents the disturbance of the conditioned reflexes during extreme physical load, induced by treadmill running. Protective action of ionol was marked by the improvement of the formation of the arising conditioned relations and their enforcement "till refusal" under maximal physical load. The possibility of antioxidant application to preventing the disturbances of the higher nervous activity is discussed.

Animals↗

[Changes in the blood flow in the cerebral cortex and hippocampus during exertion].

As demonstrate chronic experiments performed in 36 rabbits after application of physical loadings having different intensity and duration, during the process of adaptation and deadaptation, there is a close interconnection between the changes in morphological signs and the physiological data. The most profound morphological changes appear in nontrained animals under a maximal loading up to "capacity" (especially in the hemisphere cortex). The dynamics of the adaptive reactions in the hemisphere cortex and in the hippocamp are not the same: the most profound adaptive rearrangements are observed in the cerebral hemisphere cortex. During the deadaptation, the morphological changes increase.

Animals↗

[Effect of an antioxidant on the resistance of the untrained body to maximal physical loading].

Administration of the synthetic antioxidant M-1 significantly increased the animals' resistance to exercise. The maximal duration of running was increased in the animals given the antioxidant. Meanwhile fermentemia that occurred after such an exercise was almost absent and the blood lactate concentration was 2 times less than in the control, the running durations being equal. The possibility of applying antioxidants for increasing the body resistance to exercise is discussed.

Alanine Transaminase↗

[Effect of single physical exercise on formation, fixation, and reproduction of temporal associations in rats].

The effects of submaximal and maximal physical exercise on the formation, fixation and subsequent reproduction of temporary relations were compared before or immediately after training. Physical exercise before training, that impairs the formation of temporary relations, led to relatively moderate disorders in their fixation and reproduction. During physical exercise immediately after training, disorders of fixation and subsequent reproduction of temporary relations are more pronounced. It is suggested that disorders of the formation and fixation of the temporary relations caused by physical exercise are partially determined by changes in the brain content of biogenic amines.

Animals↗

[Functional status of certain subcortical brain structures during adaptation and deadaptation to physical loading].

Experiments on 35 rabbits were made to study the time course of the function of the dorsal hippocamp, reticular formation of the midbrain, ventromedial hypothalamus, caudate nucleus and anteromedial thalamus in the course of prolonged adaptation to exercise and during deadaptation. It was determined that the most considerable changes in excitability and brain blood circulation were recorded within the first 10 days of exercise. From the 20th day of the experiment, abnormalities in the function of the structures under study, except those in the hypothalamus, got stabilized, which is regarded as adaptive reaction. In the course of adaptation the periodicity of the function of the brain structures was defined.

Adaptation, Physiological↗

[Routes of blood flow away from human spinal ganglia].

Blood outflow from the spinal ganglia is accomplished along the deferent veins of the lateral part of the ganglia into the intravertebral veins (for most of cervical ganglia--into the veins surrounding the spinal cord artery), from the medial part of the ganglia--along the deferent veins into the longitudinal veins of the interal spinal plexus. Analysing total cross section area of the deferent veins of the spinal ganglia, we were able to reveal a gradual increases in cross section area from the cervical towards the lumbar veins, and a decrease towards the sacral veins. A ratio of total cross section area of the deferent veins to the volume unit of the ganglia substance characterizes capacitance density of the deferent venous bed of the spinal ganglia and is 0.01--0.014 mm2 per 1 mm3.

Adult↗

[The estimation of the carcinogenic risk in relation to anthropogenic pollution of the atmosphere].

The paper assesses an additional risk of aerogenic exposure in the establishment of a poor epidemiological situation in the context of cancer morbidity, which accounts for 2 cases per 1000 individuals in the most polluted area. The analysis made it possible to reveal the areas showing an increased additional cancer risk by individual nosological entities and to determine the directions of hygienic and epidemiological studies.

Air Pollutants↗

[Hygienic assessment of primary metallurgic processing of natural alloy ores].

The working conditions for primary metallurgic processing of naturally alloyed ores differ from those for processing magnetic iron ores in high moisture, high concentrations of CO, SO2, aerosols of Si and Cr oxides. All these factors cause high incidence rates of chronic pulmonary and cardiovascular diseases in the workers. Naturally alloyed ores produce a greater pulmonary fibrogenic action than do magnetic iron ones.

Air Pollutants, Occupational↗

[Hygienic characteristics of the influence of anthropogenic and natural geochemical factors on the population health in the South Ural].

The natural and technogenic factors of the industrial towns and rural localities in the Orenburg Region were differentially analyzed. The modifying effects of xenobiotics and their complex action on man are considered. The study showed the high pollution of the atmosphere, the blanket of snow, soil, the trace composition imbalance of drinking water, foodstuffs, a reduction in biogenic elements and an increase in toxic elements in the children's substrates (blood, hair) and high morbidity among the children suggest the presence of the formed technogenic biogeochemical province in the Eastern zone and, those in terms of some xenobiotics, in the Central area of the Orenburg Region.

Child↗

[Hygienic aspects of air pollution by sulfur-containing compounds].

The physiological and biochemical states of children and adults who resided in the vicinity of the sulphide-containing gas processing plant were studied. The chemical agents emitted by the plant were found to have adverse effects of the children's functional status, namely, decreased vital capacity of the lung, mental performance, retarded sensomotor responses, altered enzymatic system activity.

Adolescent↗

[Contribution of physical factors to the complex anthropogenic load in an industrial town].

The paper provides evidence for the increasing significance of noise and electromagnetic fields. The correlation coefficients between urban noise and the incidence of digestive diseases were found to be 0.84, those between noise and complication pregnancy were 0.83, those between noise perinatal pathology was 0.79, those between electromagnetic exposure (EME) and neuropsychopathy, EME and cataract, and EME and circulatory disorders were 0.71, 0.91, and 0.78, respectively.

Adult↗