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Biomedical subjects

V Menon

Publications and source records attributed to V Menon.

At least 127 records · Page 7Linked to original sources
PubMed1983

Luteinizing hormone releasing hormone analogue in treatment of hypergonadotrophic amenorrhoea.

The effect of a luteinizing hormone releasing hormone analogue (HOE 766) was studied in four patients with hypergonadotrophic amenorrhoea (resistant ovary syndrome). After an initial phase of stimulation, there was a uniform and sustained suppression of gonadotrophin concentrations in all the patients during the 20-24 days of treatment, presumably due to down-regulation of the pituitary receptors. One patient ovulated after stopping treatment.

Adult↗
PubMedDate not supplied

Functional brain imaging study of mathematical reasoning abilities in velocardiofacial syndrome (del22q11.2).

PURPOSE: Children with velocardiofacial syndrome (VCFS) often have deficits in mathematical reasoning. Previous research has suggested that structural abnormalities in the parietal lobe region might underlie these deficits. The present study utilized functional magnetic resonance imaging (fMRI) to explore the relationship between brain function and mathematical performance in VCFS. METHODS: Eight children with VCFS and eight comparison subjects underwent fMRI scanning and completed an arithmetic computation task. RESULTS: In the VCFS group, increased activation was observed in the left supramarginal gyrus (LSMG) as the task difficulty increased. CONCLUSION: Aberrant LSMG activation, possibly due to structural deficits of the left parietal lobe, may explain decrements in arithmetic performance observed in VCFS.

Adolescent↗
PubMedDate not supplied

Polaroid scotometer: a new device to chart suppression scotomata.

Suppression, an active inhibition of vision in one eye under binocular conditions, is a sensory adaptation in concomitant strabismus. The characteristics and extent of suppression differ not only in different types of strabismus but also in the same type under different testing conditions, which may differ in their degree of dissociation. The findings in exodeviations have thus varied from regional suppression to hemiretinal trigger, and in esodeviations from two point scotoma to single large scotoma. There is a need for a simple but less dissociative test to chart the fields under binocular conditions. We have devised a new, simple instrument based on polaroid dissociation. The findings corroborate the findings of more sophisticated tests like phase-difference haploscope.

Humans↗
PubMedDate not supplied

Effectiveness of mitomycin C in reducing reformation of adhesions following surgery for restrictive strabismus.

PURPOSE: To evaluate the efficacy of mitomycin C in reducing reformation of adhesions following surgery for restrictive strabismus. METHODS: Sixteen patients with restrictive strabismus resulting from trauma, retinal detachment surgery, and multiple squint surgeries were randomized to either a mitomycin group (8 patients) or a control group (8 patients). Mitomycin C (0.2 mg/mL) was applied intraoperatively for 5 minutes after release of adhesions. Range of passive ductions was scored for comparison. Postoperative follow-up ranged from 3-18 months. RESULTS: Compared to controls, the mitomycin C group had better range of passive ductions. There were no complications related to the cornea, intraocular pressure, uveitis, or muscle disinsertion in the mitomycin C group. CONCLUSION: Intraoperative application of mitomycin C (0.2 mg/mL for 5 minutes) is a safe and effective adjunct to surgery in the treatment of restrictive strabismus.

Adolescent↗
PubMedDate not supplied

Cyclic vertical squint.

A rare case of cyclic vertical squint which developed after surgery on medial rectus muscle and its subsequent management by the Faden operation is described.

Adult↗
PubMedDate not supplied

Congenital nystagmus with head posture (a modified approach in surgical management).

The surgical methods for correction of an abnormal head posture in congenital nystagmus presently in use, do not correct the head posture adequately and in some cases produce a postoperative tropia. We felt that this may be related to the arbitrary quantities of surgery suggested by various workers. We have observed that surgery on the medial rectus is approximately one and a half times as effective as on the lateral. Using this ratio, excellent results have been obtained in 5 cases which are reported herein.

Adolescent↗