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Biomedical subjects

V N Medvedev

Publications and source records attributed to V N Medvedev.

At least 55 records · Page 3Linked to original sources

[Cortisol content in the blood plasma in lung cancer].

Under examination were 25 patients with lung cancer. It was found that the cortisol level in blood plasma was significantly higher in the patients than in healthy subjects (in patients--20.99 mkg/100 ml +/- 1,36, in healthy subjects--12.73 +/- 1.12, p less than 0.001). In a favourable course of the disease the cortisol level in lung cancer patients after the combined or radiotherapy was reliably reduced. An increased cortisol level in blood plasma after the treatment was followed (3--6 months later) by the appearance of metastases and the cancer process generalization.

Adult↗

[Adrenal cortical function in the combined treatment of lung cancer].

Ninety five patients with pulmonary cancer were investigated. It was found that in lung cancer a correlation of total 17-ketosteroids and 17-oxycorticosteroids is changed on account of decreased androgenic hormones and increased glucocorticoid hormones. A response to the operative trauma is not the same in different objects. Following radiotherapy in most patients a reliable inhibition of the glucocorticoid function of the adrenal cortex was observed.

17-Hydroxycorticosteroids↗

[Droperidol, seduxen, fentanyl: a study of immune reactions in vitro].

Clinical concentration of droperidol, seduxen, fentanyl were studied for their effects on in vitro immunity reaction with lymphocytes from donors and patients with lung carcinoma. In the donors, the agents caused no changes in E- and EAC-rosette formation. In the patients with lung carcinoma, droperidol elevated the number of theophylline-sensitive T lymphocytes, lowered theophylline-resistant ones and eventually normalized a theophylline-resistant to theophylline-sensitive T cell ratio. Fentanyl, 5 ng/ml was demonstrated to increase amounts of early T lymphocytes. Fentanyl concentrations (5 and 25 ng/ml) decreased B lymphocytes. It was concluded that droperidol produced a positive action and fentanyl showed heterogeneous effects on E- and EAC-rosette formation in patients with lung carcinoma.

Adult↗

[Clamps for cardiovascular surgery of children].

Brief information on auricular clamps, rack-type clamps for temporary hemostasis of blood vessels, clamps for compressing and joining aortal ends together, clamps for catching blood vessels is given. The instruments are available in 12 types, all are atraumatic and easy to use.

Cardiovascular Surgical Procedures↗