[Various unsolved problems of present-day internal medicine].
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Disease↗
Biomedical subjects
V N Mineev
Publications and source records attributed to V N Mineev.
[Reasons for altered leukocyte adrenoreactivity in bronchial asthma].
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Asthma↗
[Detection of disorders in lymphocyte adrenoreactivity in bronchial asthma].
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Adrenergic beta-Agonists↗
[Characteristics of cyclic nucleotide metabolism in the leukocytes of patients with bronchial asthma].
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Asthma↗
[Errors in the diagnosis of acute diffuse glomerulonephritis in elderly patients].
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Adult↗
The specific binding of beta-adrenergic ligands and morphofunctional properties of erythrocytes in bronchial asthma.
Peripheral blood erythrocytes from patients with bronchial asthma (BA) and preasthma (PA) were investigated using the following methods: 1) the radiochemical method for determining the specific binding of beta-adrenergic ligands; 2) direct erythrocytometry for erythrocyte diameter; and 3) the cytochemical method [paraldehyde fuchsin (PAF) reaction] for membrane glycoproteins. The specific binding of beta-adrenergic ligands in erythrocytes was decreased in BA and PA patients. The number of erythrocytes of small diameter (ESD) showed a tendency to increase in patients with atopic BA and extrapulmonary allergies, as well as in healthy subjects with a family history of atopy. The percent of PAF-negative erythrocytes was found to be considerably increased in atopic BA. It is concluded that general disorders of the membrane-receptor system are a fundamental cause of reactivity changes in allergy.
Adolescent↗