PubMed Health⌕ Search

Biomedical subjects

V T Babes

Publications and source records attributed to V T Babes.

At least 19 recordsLinked to original sources
PubMed1993

Viral hepatitis in Bucharest.

A seroprevalence survey of viral hepatitis was conducted in Bucharest, Romania, between April and July 1990 on a systematic sample of 1355 persons drawn from the general population and groups at higher risk of infection. Sera were tested for hepatitis A, B, and C (HAV, HBV and HCV, resp.) markers using an enzyme-linked immunosorbent assay (ELISA) method. The prevalences of HAV and HBV markers were high in all groups. A total of 47% of the adults from the general population and 39.8% of the children aged 0-16 years had at least one HBV marker. Of the pregnant women 7.8% were positive for hepatitis B surface antigen. Among infants (0-3 years of age) living in orphanages, the prevalence of at least one HBV marker was 54.6%. The findings also confirmed that HCV was circulating in Romania. The results are consistent with national surveillance data and confirm that viral hepatitis is a major public health problem in Romania. Preventive measures will have to include HBV immunization of infants, with an appropriately targeted immunization strategy being determined through further epidemiological studies.

Adolescent↗
PubMed1977

Correlations between anti-albumin antibodies and HBsAG in hepatic patients.

A new category of autoantibodies--antipolymerized albumin antibodies (AAA)--was discovered in 1974. Studies performed from 1974 to 1976 showed their diagnosis and prognostic values in hepatic diseases; the AAA tests [immunodiffusion (ID) and hemagglutination (HS)] made possible a good estimation of the total liver cell function. Without being specific for a viral hepatitis B infection, highly significant linear correlations were found for AAA precipitin and agglutinin positivities with presence of HBsAg. High titre of AAA agglutinins unaccompanied by a positive ID test, characterise the "healthy carrier" of the HBsAg, while the isolated AAA positivity in ID is met in more severe, long-standing hepatic diseases.

Acute Disease↗
PubMed1977

ABO blood groups and HBs AG subtypes and titers in healthy carriers.

The investigation covered 457 'healthy' HBsAg carriers detected following a screening by CEP. HBsAg in the sera of these subjects were subtyped by ID and titrated by CEP. The results obtained were analyzed according to the cases investigated. Differences were found between the distribution of blood groups among the normal unselected population and among 'healthy' carriers, where the incidence of AB subjects was much higher. The difference was more marked for the carriers of HBsAg/ad.

ABO Blood-Group System↗
PubMed1975

Some particularities of hepatitis B-antigen subdeterminants.

From 200 acute viral hepatitis patients serum samples were collected successively, at various intervals. In 192 patients one single hepatitis B-antigen (HB-Ag) subdeterminant ("ad" in 37.6% and "ay" in 62.4% of the cases) occurred and persisted during the entire course of the disease. The remained 8 patients (4%) showed an alternation of HB-Ag subdeterminants. The possible causes of this alternation are discussed in detail.

Epitopes↗
PubMed1975

[Hepatitis beta-antigen titer and subtypes of acute and chronic hepatitis].

The incidence of the hepatitis B antigen (HBSAg) in the sera of 650 acute virus hepatitis (AVH) and 200 chronic hepatitis (CH) patients was determined by screening test (counter-immunoelectrophoresis and immunodiffusion). The findings showed a positivity in 28% of the acute virus hepatitis patients and in 47% of the chronic hepatitides. Further, the detected HB Ag was investigated both quantitatively (titer) and qualitatively (subtype). The results obtained have shown the absence of differences in the HB Ag-titer distribution of the two groups investigated and the prevalence of the HBSAg/ayw subdeterminant in both groups (62% in AVH and 57% in CH patients).

Acute Disease↗
PubMedDate not supplied

Apparently healthy HBs antigen carriers: ABO blood group distribution and ay : ad ratio.

HBs antigen (HBsAg) incidence and subtype ratio were studied in apparently healthy HBsAg carriers and correlated with the ABO blood group of the subjects investigated. The incidence of subjects belonging to blood group AB was higher among the healthy carriers than in the unselected normal population, and the ay : ad ratio was much lower in this blood group than in the other ones.

ABO Blood-Group System↗
PubMedDate not supplied

[B viral hepatitis as a risk factor for clinical laboratory personnel].

A study was carried out on the risk of contamination with viral hepatitis B for the personnel of the clinical laboratories who handle blood samples with HB Ag and HB Ac, collected from the patients. Of the total 1945 blood samples collected from 639 adult patients, 74 were serologically positive (3.8%) of which 39 HB Ag carriers (2%) and 35 HB Ac carriers (1.8%). Although these proportions are close to those found in the normal population the risk of contamination of the laboratory personnel is greater owing to the direct contact with the pathologic product and the impossibility of recognizing the HB Ag and Ac positive samples before testing. The risk may be lowered by strict compliance with the general rules of hygiene, by avoiding especially any microtraumas of the hands, by automatic pipetting of the sera and reagents and the use of sterilized materials (particularly in haematologic and biochemical laboratories.

Hepatitis A↗
PubMedDate not supplied

Apparently healthy HBsAg carriers: sex-dependent difference in ABO blood group distribution, subtype ratio and antigen titer.

The results obtained by subtyping and titration of 872 HBsAg from apparently healthy carriers were grouped according to blood group and sex. The incidence of blood group AB is higher among healthy HBsAg carriers than in the unselected population. There are large variations as regards the ay : ad ratio (overall mean value : 4.74) : minimal ay : ad values occur in the AB blood group, both in men (4.00) and in women (1.33), as compared with the mean values of 5.07 and 2.95 recorded in men and women, respectively. Titer analysis shows a cluster of higher titers in women. The involvement of immunogenetic mechanisms in asymptomatic HBsAg carriage is suggested.

ABO Blood-Group System↗