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Biomedical subjects

V Talwar

Publications and source records attributed to V Talwar.

At least 55 records · Page 3Linked to original sources

Bacteriology of ophthalmic infections with special reference to anaerobes.

A total of 138 eye specimens were processed for aerobic and anaerobic cultures. Clinical data were obtained from 50 patients with unilateral ophthalmic infection. Cultures from the uninfected eye of 38 of these 50 patients were also processed for comparison. In addition, 50 cultures were obtained from one or both eyes of 30 healthy controls who had no eye infection. Anaerobes and aerobes were isolated from infected eyes of 6 (12%) and 37 (74%) patients respectively. No growth was observed in infected eye of 8 (16%) patients. A mixture of aerobes and anaerobes were recovered only in 2 cases. Of the total 47 aerobic isolates from infected eye specimens, Staphylococcus aureus (11), coagulase negative staphylococci (12) and Streptococcus pneumoniae (9) were predominant isolates. Six anaerobes isolates included Gram positive nonsporing anaerobic bacilli (4 including Propionibacterium acne) as predominant isolates. Clostridium perfringens was isolated from a case of post operative endoophthalmitis. From the uninfected eye of same patients though the number and types of aerobic bacteria were similar, none grew any anaerobes. Aerobic and anaerobic bacteria were isolated in 70 and 6 per cent of eye swabs respectively from the healthy controls.

Bacteria, Aerobic↗

Multi drug resistant Salmonella typhi infection: clinical profile and therapy.

Multiple drug resistant Salmonella typhi infection was observed in thirty five recent cases among forty eight children with bacteriologically proven enteric fever. Incidence of complications such as shock, myocarditis, encephalopathy and paralytic ileus was higher among these. A combination of cephalexin and gentamicin was successfully used in the management of these children.

Amoxicillin↗

The problem of emerging chloramphenicol resistance in typhoid fever--a preliminary report.

Drug sensitivity of Salmonella typhi isolated from 25 blood culture positive cases of typhoid fever who presented between May and July 1990 was tested to determine their in vitro susceptibility to various antimicrobials. Twenty-one of them (84%) showed resistance to chloramphenicol and 24 (96%) to cotrimoxazole. All the 25 cases were sensitive to norfloxacin, gentamicin and cephalexin. Sixteen of 21 chloramphenicol resistant typhoid cases in whom chloramphenicol was initially started failed to respond to this drug even after 5 to 7 days, thereby indicating that in vivo response matched with the in vitro sensitivity. Clinical response to norfloxacin, whether given initially or following chloramphenicol failure, was prompt and satisfactory. Norfloxacin thus appears to be a good choice in such cases.

Chloramphenicol↗

Incidence of R-plasmids in toxigenic & non-toxigenic strains of Escherichia coli from children with diarrhoea.

Toxigenic (30) and non-toxigenic (30) multiresistant strains of Esch. coli were studied for the incidence of R-plasmids. ST+, LT+ and ST+ LT+ plasmids were produced by 66.7, 30 and 3.3 per cent of toxigenic strains, respectively. ACST was the predominant resistance pattern in both the types. Incidence of R-plasmid in the toxigenic strains was 73.3 per cent as compared to 60 per cent in the non-toxigenic strains. Non-conjugative R-plasmid was present in 10 per cent of the non-toxigenic strain. In 13.3 per cent of toxigenic Esch. coli strains along with the transfer of antibiotic resistance, the ability to produce enterotoxin was also conferred on the recipient. This suggests that the genes coding for antibiotic resistance and enterotoxin are frequently associated and can be transferred together in vitro.

Child, Preschool↗