A detailed clinical study of 51 consecutive cases of neonatal klebsiella septicemia was carried out prospectively over a 20 months period. The incidence was 6.27 per 1000 live births. Majority (85.5%) were either preterms or small for date. Almost fifty percent babies had associated perinatal risk factors. Mean age of onset was 5.7 +/- 2.2 days. General symptoms were the earliest to occur at mean age of 5.7 days followed by respiratory, alimentary, hematological and neurological symptoms at 6.2, 6.3, 6.6 and 7.9 days respectively. About half of the neonates had associated complications; commoner being meningitis (20%), bleeding manifestations and sclerema (17.6% each) and pneumonia (15.7%). Cefatoxime was found to be the drug of choice (86% sensitivity). Nine babies (17.6%) died during the study period at a mean age of 9.1 +/- 3.2 days. Mean duration of hospital stay in rest of neonates was 27.9 +/- 12.1 days. Neurological symptoms were commoner in late onset disease. Bleeding manifestations, sclerema and granulocytopenia were seen exclusively in preterms. Presence of respiratory symptoms, bleeding, sclerema, shock and granulocytopenia were identified as poor prognostic factors in neonatal klebsiella septicemia.

Bacteremia↗

PubMedDate not supplied

Use of plasmid DNA analysis in diagnosis of catheter related enterococcal septicemia in a neonate.

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Bacteremia↗

PubMedDate not supplied

Cytologic diagnosis of tuberculous lymphadenitis in children by fine needle aspiration.

One hundred consecutively diagnosed cases of tuberculous lymphadenitis in children have been analysed retrospectively. All cases were stained by May Grunwald Giemsa for cytomorphology and Ziehl Neelsen stain for acidfast bacilli (AFB). In 52 cases the material was sufficient and AFB cultures were possible. A diagnosis of tuberculosis was made when smears showed epithelioid cell granulomas or AFB on either smears or culture. M. tuberculosis and atypical mucobacteria were cultured in 26 and 3 cases respectively. In 6 cases the diagnosis of tuberculosis would have been missed but for culture studies, the cytologic smears were necrotic and stains for AFB negative.

Biopsy, Needle↗

PubMedDate not supplied

Clinical and bacteriological profile of hospitalized community acquired pneumonias--a preliminary study.

The spectrum of clinical and bacteriological features of 46 cases of pneumonias presenting to U.C.M.S. and Guru Tegh Bahadur Hospital complex in East Delhi over a period of three months are presented and their etiopathogenesis discussed. The high incidence of pneumonias in admitted patients belonging to the population adjacent to the hospital is highlighted. Etiological diagnosis based on sputum culture and sensitivity tests was possible only in 37% cases, and there is need for the use of newer even though invasive methods for arriving at the bacteriological diagnosis.

Adult↗