Biomedical subjects

V V Novitskii

Publications and source records attributed to V V Novitskii.

25 records · Page 2Linked to original sources

PubMed2002

Structural abnormalities and changes in Na,K-ATPase activity in erythrocyte membranes in patients with neurotic disorders.

We studied structural and metabolic characteristics of erythrocyte membranes in 19 patients with neurotic disorders (neurasthenia and dysadaptation). Microviscosity of the lipid phase in erythrocyte membranes increased in 13 patients, and Na,K-ATPase activity decreased in 6 patients. Various changes in test parameters are probably associated with different adaptive capacities of the organism under stress conditions.

Adult↗

PubMed2002

Effect of lipid matrix and cytoskeleton proteins on Ca2+-activated K+ channels in erythrocytes of alcoholic and II type diabetes mellitus patients.

We studied the effect of changes in erythrocyte volume and irreversible thermal denaturation of cytoskeleton proteins and lipid matrix on activity of Ca(2+)-activated K+ channels in erythrocytes of alcoholic and patients with II type diabetes mellitus. Changes in Ca(2+)-dependent potassium permeability of erythrocyte membrane in alcoholic patients and patients with II type diabetes mellitus are related to modification of cytoskeleton, rather than to changes in lipid matrix.

Alcoholism↗

PubMed2002

Structural and functional characteristics of lymphocytes in chronic carriers of tick-borne encephalitis virus.

Study of the surface phenotype, structure of plasma membrane, and activity of DNA repair system in peripheral blood lymphocytes from patients with different clinical forms of tick-borne encephalitis associated with long persistence of the virus revealed a pronounced imbalance between lymphocyte subpopulations, increased microviscosity of the plasma membrane lipid phase, and decreased activity of the DNA repair system in lymphocytes.

Adult↗

PubMed2001

Ultrastructural changes in erythrocytes in patients with mental disorders.

Transmission electron microscopy of peripheral blood erythrocytes from patients with paranoid and residual schizophrenia, mental retardation, and neurotic disturbances revealed nonspecific ultrastructural changes in the membrane and matrix of red blood cells.

Adolescent↗

PubMed2001

Cytogenetic impairments of peripheral blood lymphocytes during infectious mononucleosis.

We performed chromosomal analysis and micronucleus test of peripheral blood lymphocytes during infectious mononucleosis. The content of lymphocytes with structural chromosome aberrations and micronuclei increased in patients with pronounced clinical and hematological signs of infectious mononucleosis (acute stage). There were cells with changed number of chromosomes. These cytogenetic abnormalities persisted both during convalescence and in the delayed period after recovery.

Adolescent↗

PubMed2001

Structural and metabolic state of peripheral blood mononuclear cells during infectious mononucleosis.

Morphometrical and cytochemical analysis of peripheral blood mononuclear cells from patients with infectious mononucleosis was carried out. Structural and metabolic state of lymphocytes and monocytes during convalescence and in delayed period after recovery differed from normal. Cytochemistry of atypical mononuclear cells was evaluated.

Adolescent↗

PubMed2000

Surface architectonics of peripheral blood erythrocytes in patients with mental diseases.

Scanning electron microscopy demonstrated altered surface topography of peripheral erythrocytes in patients with nonpsychotic mental diseases, nonmetabolic mental retardation, and paranoid schizophrenia. Maximum decrease in the number of biconcave diskocytes and accumulation of transitional, prehemolytic, and degenerative forms of erythrocytes were found in schizophrenia.

Adolescent↗