[Pathophysiologic basis and therapy of brain edema].
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Biomedical subjects
Publications and source records attributed to W Abdulla.
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The generally accepted principles of treatment of a diabetic as a case for operation or emergency are listed and substantiated with reference to the varied pathophysiological processes. In particular the preoperative attitude of the diabetic and the special anesthesiological problems are gone into.
The clinical results of 50 patients with retinal and vitreous surgery performed in combined electrostimulating anaesthesia are reported. Premedication consisted of a barbiturate such as medomin and of atosil, ordered the evening before surgery. 1/2 hour preoperatively 1.5--2 ml thalamonal and 0.5 mg atropine were administered intramusculary. All patients were intubated and controlled respirated; stimulation starting about 5 minutes following intubation procedure. During continuous intermittent relaxation anaesthesia was maintained by a mixture of nitrous oxide/oxygen 1:1 and electrical stimulation at the dermatoms of N. trigeminus I, II and Plexus cervicalis 3 and 4. For the first time stimulation of the dermatoms during anaesthesia was done by self adhesive electrodes. So we were able to eliminate the circumstantial and not even harmless invasivity of the needle technique. The main advantages of the new method we see in a good circulatory stability and in good postoperative cooperation of the patients. Especially in old and poor risk patients the results of transcutaneous electrostimulating anaesthesia are excellent.
Five to six millions of hypertensives live in the Federal Republic of Germany. Of these, about 70% are known to be hypertensives but only 30% are consistently treated. It is therefore not surprising that hypertension is one of the most common risk factors in patients who have to be operatively treated. The commonly approved principles of hypertensive therapy are compiled in the present study and classified with reference to the multivarious pathophysiological processes. In particular, special anesthesiologic problems are dealt with in detail. Furthermore, this paper provides the basic knowledge of the artificial fall in blood pressure under anesthetic conditions.
In spite of the great advances in anesthesia, regional anesthesia has not lost its importance. The development of new, longer-acting local anesthetics has extended its indication still more. The causes of accidents lie mostly in ignorance ofthe pharmacology of local anesthetics and their adjuvants, in faulty technical performance of the nerve blockade and last but not least in inadequate knowledge of the therapy, of the side effects and complications. The various complications of regional anesthesia are reported on and the necessary therapy dealt with.