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Biomedical subjects

W Cross

Publications and source records attributed to W Cross.

9 recordsLinked to original sources
PubMed2003

The impact of the Dornier Compact Delta lithotriptor on the management of primary ureteric calculi.

OBJECTIVE: To assess the effectiveness of the Dornier Compact Delta lithotriptor on the management of in situ primary ureteric stones. PATIENTS AND METHODS: 137 patients with primary ureteric stones were treated at a tertiary urological center using the latest Dornier Compact Delta lithotriptor between January 1999 and January 2002. Effectiveness of lithotripsy, retreatment rate, reasons for failure and complications were assessed. RESULTS: 102 males and 35 females with primary ureteric stones underwent ESWL treatment at our center. 74 patients had upper, 37 middle and 26 lower ureteric locations respectively. Mean stone size was 10 mm (range 8-25 mm). Mean numbers of sessions required were 1.8 (range 1-3). The retreatment rate was 33% in upper ureteric, 29% in mid ureteric and 26% in lower ureteric locations respectively. Complete clearance rate at 3 months was 86% for upper ureteric, 79% for mid ureteric and 79% for lower ureteric. 29 patients had auxiliary treatment in the form of double J ureteric stenting or percutaneous nephrostomies. 26 patients failed treatment and underwent ureteroscopic or ante grade percutaneous removal. Stone size was the only significant factor correlating with failure. The mean size of stones in the successful group was 12 mm as compared to 17 mm in failure group. The likelihood of success following a failed second session (no disintegration or disintegration with fragments more than 6 mm) of treatment was 13.4%. Complications including, steinstrasse, colic, UTI and petechial haemorrhage were seen in 35 patients. One patient developed pyonephrosis and subsequently required nephrectomy. CONCLUSION: An electromagnetic shock wave lithotriptor using the EMSE-150 shock wave emitter is an effective in situ treatment of primary ureteric stones. Patients with large stone size are likely to have a higher retreatment rate, more auxiliary procedures and complications. Having a failed second treatment session, the likelihood of a successful outcome after third session of ESWL is poor.

Adolescent↗
PubMed2003

Bladder reconstruction--from cells to materials.

Surgical reconstruction of the urinary bladder is performed on patients of all ages for a diverse range of conditions, including congenital abnormalities, bladder dysfunction, trauma and cancer. The most common material utilized to augment or replace the bladder during these procedures is a segment of the patient's own intestine. However, this procedure ('enterocytoplasty') is associated with significant clinical complications that arise due to the exposure of the epithelial lining of the intestine to urine. A number of alternative approaches are being actively developed to find a practical and functional substitute for native bladder tissue. These range from 'composite enterocystoplasty', where the de-epithelialized intestine wall is lined with bladder epithelial cells that have been propagated in vitro, to augmenting the urinary system with natural or synthetic biomaterials that may incorporate in vitro-propagated cells. However, if tissue-engineered products are to have therapeutic application in bladder reconstruction, a number of issues remain to be addressed; these issues are discussed briefly below.

Bioartificial Organs↗
PubMed2001

Theory behind surgical correction of presbyopia.

This relatively new procedure is interesting, promising, and appears to be safe. These issues are currently being evaluated by the US FDA and in several other countries, most notably Canada. The procedure is based on Ronald A. Schachar's new theory of how accommodation occurs. The clinical course of the patients and the new wavefront analysis appear to support the theory. Regardless of the exact mechanism, clinically, the patients read and behave as though they have had their accommodation restored. The author certainly has been very impressed and excited with the results in his patients whose surgeons he has proctored.

Accommodation, Ocular↗
PubMed1975

The triple pulse generator: Clinical evaluation of a new multipurpose external pulse generator.

This report describes our experience with a new, versatile battery operated, multi-purpose pulse generator especially designed for the electrophysiological investigation and treatment of cardiac arrhythmias in man. The unit was constructed according to our specifications and has been clinically in 75 patients over a period of 18 months. We have found the triple pulse pacemaker safe, reliable and functioning precisely according to specifications both clinically and when repeatedly checked with a storage oscilloscope.

Arrhythmias, Cardiac↗