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Biomedical subjects

W Dölle

Publications and source records attributed to W Dölle.

At least 19 recordsLinked to original sources

[Internistic therapy of acute diverticulitis].

Diverticular disease of the large bowel is very common in Western societies. The clinical pattern reaches from uncomplicated diverticular disease to acute peridiverticulitis, that ultimately afflicts about one in four patients having colonic diverticulosis. The illness may be indolent or fulminant, depending on the degree of colonic spillage and its containment. Therapy is usually medical and consists of "resting" the bowel, administering antibiotics and analgetics. Surgery is reserved for recurrent acute attacks, diffuse peritonitis, abscesses, fistulas, severe diverticular hemorrhage or obstruction. A diet rich in fibers reduces infectious complications.

Acute Disease

[Pathogenesis and clinical aspects of primary liver cell carcinomas].

The hepatocellular carcinoma is the most frequent primary liver cell carcinoma. On account of its geographical distribution with preferential occurrence in China, SE Asia and South Africa, exogenic causes are thought to be mainly responsible for its aetiopathogenesis. Besides mycotoxins, the hepatitis B virus infection (HBV) is particularly important. Integration of HBV-DNS into the hepatic cell DNS is considered to be an initiatory step in hepatocarcinogenesis. Clinically the tumour usually becomes manifest by upper abdominal complaints. Curative treatment can be promising only with very small tumours which can be detected most safely via ultrasound examination and alpha-1-fetoprotein determination.

Carcinoma, Hepatocellular

[Laser sclerostomy: an alternative to current surgical filtering procedures. Experimental studies].

A new filtering procedure, laser sclerostomy, was performed in 12 rabbit eyes by combined application of an argon and a YAG laser. In 10 cases an open fistula connecting the anterior chamber and the subconjunctival space could be demonstrated histologically. As neither the conjunctiva nor the globe are incised "ab externo," the possibility of an intraoperative infection is excluded and the risk of postoperative scar formation is minimized. Consequently, laser sclerostomy promises a new approach to glaucoma control in human eyes, too.

Animals

[Ocular outflow resistance and rate of secretion of aqueous humor following iridotomy and posterior capsulotomy with the Nd:YAG laser].

When the Nd:YAG laser is used for iridotomy and posterior capsulotomy an elevation in the intraocular pressure (IOP) is often found within the first few postoperative hours and in some cases for even 1-3 days. In 39 eyes the changes in postoperative intraocular pressure were noted and the preoperative as well as the postoperative outflow facility and aqueous secretion flow measured by oculopressiontonometry. The results demonstrated that in both iridotomy and posterior capsulotomy a reduction in the outflow facility caused the postoperative rise in IOP. Aqueous secretion flow did not increase. Most iridotomy patients had glaucoma and consequently reduced preoperative outflow facility. This determined the postoperative IOP elevation. In capsulotomy patients, no such correlation was evident, but the role of the laser energy applied seems to be more important according to our results.

Aqueous Humor