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W Distler

Publications and source records attributed to W Distler.

At least 73 records · Page 4Linked to original sources
PubMed1981

Serum levels of oestradiol-15 beta and luteinizing hormone related to follicular growth as monitored by ultrasound in women with normal menstrual cycles.

Serum levels of oestradiol-15 beta (Oe2), luteinizing hormone (LH) and progesterone (P) in 20 healthy women were correlated to the size of the ripening follicle during the follicular phase of normal menstrual cycles. Growing follicles were measured by ultrasound using the full bladder technique. In each individual case a good correlation (r = 0.88) between the Oe2 values and the size of the maturing follicle was found. However, since all women examined ovulated at a different Graafian follicle diameter (range 17 to 26 mm), the corresponding Oe2 values showed quite a large variation (range 0.78 to 2.5 nmol/l). The cervical score correlated to follicular maturation up to a follicle size of 19 mm (maximal cervical reaction). From there on no further improvement of the cervical parameters could be observed. We conclude that ultrasound monitoring of follicular growth can be a useful addition to the Oe2 and P measurements in the clinical management of the infertile woman. Bifollicular maturation can be diagnosed early, when the endocrinological data are combined with follicle size. Moreover, a correlation can be made between follicular growth and oestradiol production in the individual cycle.

Adult↗
PubMed1980

[Critical analysis of the early perinatal morbidity at the department of obstet. gynecol. in Düsseldorf (1975-1977) (author's transl)].

A retrospective investigation of 219 deliveries (of 2870 deliveries between 1975-1977) with Apgar-scores less than or equal to 6 at 1 minute or UA-pH-values less than or equal to 7,15 is presented. Therefore the case histories of 75 spontaneous deliveries, 69 breech or forceps deliveries, and 75 cesarean sections were reviewed. Analysis of our data shows that in 32% of the spontaneous deliveries, in 61% of the breech or forceps deliveries, and in 29% of the cesarean sections the low Apgar- and UA-pH-values seemed to be avoidable. However, the comparison of 1973-1974 and and 1975-1977 gives evidence that the percentage of Apgar-scores less than or equal to 6 at 1 minute or UA-pH-values less than or equal to 7,15 decreased from from 13% to 8%. Also the incidence of severe acidosis of the newborn (UA-pH less than 7,10) was reduced from 2,3% to 0.8%. Further prevention of early perinatal morbidity and improvement of fetal outcome seems to us possible by: 1. the reduction of premature deliveries, 2. a greater application of the intermittent intrapartal tocolysis to avoid mid forcipes, 3. an intensive training for the objective interpretation of cardiotocography.

Acidosis↗
PubMed1980

[Reciprocal in vitro actions of Streptococcus mutans, Actinomyces and Veillonella: a simplified model for carbohydrate metabolism in plaque].

Different acids can be found in vitro, if glucose is metabolized in plaque or by different combinations or oral bacteria: 1. Streptococcus mutans and Actinomyces do not show interactions concerning metabolism and formed acids. 2. Streptococcus mutans and Veillonella after short incubation time produce lactate; after long time of incubation acetic and propionic acid are main products and lactic acid diminishes. 3. Actinomyces and Veillonella react similar to Streptococcus mutans and Veillonella. Succinate produced by Actinomyces is fully utilized by Veillonella.

Actinomyces↗
PubMed1979

[Prenatal sex determination by radioimmunoassay of testosterone with and without chromatography of the amniotic fluid (author's transl)].

Amniotic fluid testosterone measured by radioimmunoassay (RIA) without chromatography (immunoreactive testosterone) seems not to be a definitive test for prenatal sex determination in all cases. In this study testosterone (T) levels measured by RIA with chromatography of the amniotic fluid samples were compared with immunoreactive testosterone (iT) values, to determine the predictive accuracy of the two methods. In 111 amniotic fluid samples between 15 and 19 weeks of gestation iT and T were measured parallelly. There are significant differences between iT- and T-means of both sexes (p less than 0.001). 95%-condifence limits of iT-values of the male and female fetuses are largely overlapping. In contrast, the overlap of 95%-confidence limits of the T-values is only minor. The measurement of testosterone with chromatography of the amniotic fluid samples shows for prenatal sex determination in over 90% accuracy. This result is due to the elimination of sex-specific differences in crossreacting steroids within the amniotic fluid of both sexes.

Amniotic Fluid↗
PubMed1979

[Comparison of the metabolism of isolated streptococci and dental plaque].

1. Isolated cultures of Streptococcus mutans form lactic acid as well as small amounts of formic acid and acetic acid during the anaerobic break down of glucose. The composition of the acids in terms of percent is independent of time. 2. Plaque specimens incubated in vitro show a complicated spectrum of substances; propionic and butyric acids are found in addition to lactic, formic, and acetic acids. The composition in terms of percent depends on the incubation period. The percentage of lactic acid drops as the incubation period is extended. 3. Just as the plaque, the product spectrum of isolated streptococci in terms of quantitative composition depends on the buffer capacity.

Acetates↗
PubMed1978

Log normal distribution of ovarian and placental steroid values in early human pregnancy.

Concentrations of estradiol, progesterone, 17OH-progesterone were measured by radioimmunoassay in individual serum samples obtained from a group of 304 women with normal gestations between the 4th and 17th week of pregnancy. Values obtained underwent statistical analysis in order to determine the arithmetic mean and the 95% normal range (+/- two standard deviations). It was noted hereby that the spread of values above the mean was greater than that below the mean, and that very often the mean minus two standard deviations was either close to zero or negative. Therefore, the data for each hormone were analyzed for normality of the distributions by the chi-square test. For each hormone the chi-square test was significantly different (p less than 0.001) from the normal distribution (Gaussian). Subsequently, linear transformation by rankit analysis revealed the log-normal distribution of our data. Furthermore, rankit analysis was used as a graphical method to delineate a useful clinical range, which includes the mean and meaningful 95% confidence limits for estradiol, progesterone, and 17OH-progesterone in early normal pregnancies.

Estradiol↗
PubMed1978

[Intra and extracellular acid spectrum of plaque incubated in vitro].

1. The different in the substance spectrum of incubated plaque produced by the change from glucose to sucrose is insignificant. 2. A variation in the buffer capacity, such as is typical for cariogenic plaque in vivo, markedly influences the proportional composition of the acids formed. 3. The product spectrum of a mixed bacteria population such as in plaque is time dependent. The reason for this dependence is probably the interaction of the individual types of bacteria with each other. 4. The spectrum of acid composition extracted from the plaque is different from that in the vicinity of the plaque.

Acids↗
PubMed1976

Estriol in pregnancy. IV. Normal concentrations, diurnal and/or episodic variations, and day-to-day changes of unconjugated and total estriol in late pregnancy plasma.

Normal values of unconjugated, total, and immunoreactive (measured without extraction) plasma estriol (E3) have been determined from radioimmunoassay data obtained in 217 uncomplicated third-trimester pregnancies. Small but significant diurnal variations in unconjugated and total plasma E3 have been observed in a study comprising 12 women who were hospitalized during late pregnancy for diabetes, toxemia, or placenta previa. The late morning decreases in unconjugated and the afternoon/evening decreases in total plasma E3 concentrations, averaging some 10 to 15 per cent, were overshadowed by considerable episodic fluctuations and may thus be clinically irrelevant. Day-to day changes of unconjugated and total plasma E3 concentrations in late pregnancy were similar and smaller than changes in urinary E3 measurements. The urinary E3/creatinine ratio, however, reducing inadequacies of 24 hour urine collections, varied less than unconjugated or total plasma E3. The data suggest that a decrease in unconjugated or total plasma E3 must exceed 40 to 45 per cent of the mean of the three preceeding determinations if it is to be considered a signal of fetal distress.

Activity Cycles↗