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Biomedical subjects

W Künzel

Publications and source records attributed to W Künzel.

At least 199 records · Page 11Linked to original sources
PubMed1985

Repetitive reduction of uterine blood flow and its influence on fetal transcutaneous PO2 and cardiovascular variables.

The influence of repeated asphyxia on fetal transcutaneous PO2, relative local skin perfusion, heart rate, blood gases and pH was investigated in 15 experiments on 8 acutely instrumented sheep fetuses in utero between 125 and 145 days gestation (term is 147 days). Uterine blood flow was intermittently arrested (11 times within 33 min) by intra-vascular maternal aortic occlusion, exposing the fetuses to repeated episodes of asphyxia of 30 (n = 3), 60 (n = 9) and 90 (n = 3) s duration. The fetal transcutaneous PO2 fell as the duration of asphyxia (2 alpha less than 0.01), heart rate deceleration area (2 alpha less than 0.01) and acidaemia (2 alpha less than 0.01) increased. With decreasing skin perfusion, which was dependent on the duration of asphyxia (2 alpha less than 0.001) and acidaemia (2 alpha less than 0.001), a discrepancy developed between transcutaneous and arterial PO2. The increase (delta) in transcutaneous-arterial PO2 difference was related linearly to the duration of asphyxia (2 alpha less than 0.01), the mean haemoglobin oxygen saturation (2 alpha less than 0.001), acidaemia (2 alpha less than 0.001) and relative local skin flow (2 alpha less than 0.05). It was highest after severe episodes of asphyxia (90 s), when O2 saturation, skin blood flow and arterial blood pH values were low. Fetal heart rate deceleration area was only correlated with the cutaneous-arterial PO2 difference when the mean fetal haemoglobin oxygen saturation was below 35%. Thus, a discrimination of heart rate decelerations that are significant for the fetus seems to be possible, when associated with low transcutaneous PO2 values. We conclude that in the sheep fetus transcutaneous PO2 measurements during repeated asphyxial episodes yield information on fetal oxygenation and on the skin vasomotor response.

Acid-Base Equilibrium↗
PubMed1984

[Amputation neuroma as a rare cause of so-called post-cholecystectomy syndrome].

At the instance of a 30-year-old female patient a casuistic contribution to the differential diagnosis of the so-called "postcholecystectomy syndrome" by means of ERC is given. On condition after cholecystectomy an amputation neuroma had again led to colics. Amputation neuromas are rare, but not unknown causes for complaints after operations at the bile ducts. The origin of such a neuroma at the extrahepatic bile ducts is discussed.

Adult↗
PubMed1984

Effects of comprehensive preventive programmes on oral health in children and juveniles in congested industrial areas.

For the attainment of oral health for all by the year 2000 WHO and FDI have together established specific goals. Global indicators formulated for various age groups can be achieved by nationally devised and regionally realized programmes. Prospects for the attainment of these goals are higher in those countries in which dental health has been integrated into a system of medical health care. Legal requirements, where they exist, are helpful in putting preventive programmes into operation. On this basis wide-reaching preventive programmes for 3-18-year-olds have been introduced in the past 20 years in various industrialized countries. Frequently, well developed systems of treatment provide the foundation for these preventive services. Fluoride intake from water, salt or tablets is combined with controlled oral hygiene, topical applications or oral rinses with fluoride-containing solutions and uncontrolled use of fluoridated toothpastes. Special attention is directed to oral health education and sugar restriction in the snacks taken between meals. The effectiveness and efficacy of the different preventive measures are analysed by resorting to the experience gained in the German Democratic Republic and to reports of results obtained with preventive programmes in other countries. From this survey the global indicators of oral health for the 5-6, 12 and 18-year-olds must be considered realistic for they can be met by a systematic approach on a population-wide basis.

Adolescent↗