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Biomedical subjects

W Kumpan

Publications and source records attributed to W Kumpan.

At least 55 records · Page 3Linked to original sources

[Role of computed tomography in malignant tumors of the oral cavity and pharynx].

The CT findings of 22 patients with histologically verified malignant tumors of the oral cavity and pharynx were evaluated to demonstrate the value of CT. Comparison with conventional radiological methods was made. In 16 patients an attempt was made to define tumor expansion and 6 patients were examined after surgery and radiation therapy with regard to tumor recurrence. In the first group we found tumors of different stages: in advanced cancer it was evident that with CT it is possible to describe tumor expansion very exactly and its relationship to surrounding structures, as well as the invasion of the intracranial space or spinal cord. In malignomas of the tongue and mouth floor measurements of size by CT were very precise, as proved by surgery. Our results in the first group of patients show, that CT has a great influence on therapeutic management and is also very important for clinical staging of these malignomas. In the second patient group it is shown that by CT differentiation between postoperative changes and recurrent tumor is as difficult as it is in other organs. Based on the postoperative examination, appropriate follow-up is necessary.

Adult↗

[Differential diagnosis of cholestasis by non-invasive methods--comparison of cholecysto-cholangiography, ultrasonics and hepatobiliary sequential scintigraphy].

The value of the three non-invasive morphological methods--cholangiography, sonography, and cholescintigraphy--in the differential diagnosis of "surgical" and "non-surgical" cholestasis was assessed prospectively in 28 patients. The main disadvantage of cholangiography was the large number of patients (11 out of 28) in whom the biliary tract could not be visualized. Correct diagnosis was achieved by sonography in 25 out of 28 and by cholescintigraphy in 23 out of 28 patients.

Bile Ducts, Intrahepatic↗

Radiography and bone scintigraphy in multiple myeloma: a comparative analysis.

The sensitivity of radionuclide imaging for detecting skeletal lesions was compared with that of radiography by evaluating 573 different anatomical sites in 41 patients with multiple myeloma. Radiography revealed a significantly greater number of myeloma-related bone lesions than did radionuclide imaging. Of the 179 myeloma-related bone lesions detected when both techniques were applied, 163 were seen by radiography and 82 by radionuclide imaging. Ninety-seven lesions were detected by radiography alone and 16 lesions seen by scintiscanning only, yielding a sensitivity of 91% for the former and of 46% for the latter technique. Radionuclide imaging proved superior to radiography only occasionally in the rib cage, and rarely in other anatomical sites. These findings suggest that radiography is the method of first choice in obtaining a skeletal survey in patients with multiple myeloma. In cases with continued pain, unexplained by standard radiography, the skeletal survey should be supplemented by tomography and radionuclide imaging.

Bone and Bones↗

A further case of submucosal lymphangioma of the duodenum diagnosed during endoscopy.

Submucosal lymphangiomas are benign tumors which rarely occur in the gastrointestinal tract. The current report describes the tenth case of a submucosal cavernous-cystic lymphangioma of the duodenum. The diagnosis was made during endoscopy and was confirmed histologically in a biopsy specimen. Following a brief review of the localization and symptoms of submucosal lymphangiomas of the gastrointestinal tract published thus far in the literature, therapeutic considerations are discussed.

Aged↗

[Results of postoperative radiotherapy in breast cancer (author's transl)].

The results are presented of postoperative irradiation in the treatment of breast cancer at the Department of Radiotherapy and Radiobiology, University of Vienna. Our data compare well with the best results reported in the literature. Apart from the importance of high loco-regional freedom from disease for the quality of life of these patients, the related increase in survival prospects is stressed.

Breast Neoplasms↗

[The value of postoperative irradiation in the curative management of breast cancer (author's transl)].

A report is presented of the value of post-operative irradiation in patients with operable breast cancer. A combination of conservative surgery followed by irradiation provides optimal loco-regional results. Improved 10-year survival rates have already been reported with adequate irradiation of the peripheral lymphatics. The location and size of the primary tumour, as well as exact quantitative statements about histologically positive axillary lymph nodes are parameters of utmost importance.

Breast Neoplasms↗

[Bisectorial small-angle pendulum irradiation alternatively to other methods of 60Co-teletherapy: valence and volume doses (author's transl)].

A comparison is made between five irradiation methods, the dose distribution and volume doses of which had been ascertained by means of two phantoms presupposed differently large. Of the two methods of small-angle pendulum irradiation, the bisectorial monaxial pendulum technique turns out to be a practicalbe alternative to fixed-field and rotation irradiations. Similarly to fixed-field irradiation with two opposed fields, to which, after all, this technique is superior in every respect, it makes possible a relatively simple spatial irradiation planning. In this regard it is also more favorable than the rotation irradiations, though they give security of a more homogeneous load to axially parallel focuses; but an oblique position of the focal axis can be compensated only by an extension of the target volume and consequently augmentation of the volume dose. The necessity of confining to a certain extent the sum of absorbed energy is accentuated.

Cobalt Radioisotopes↗

[Results of postoperative radiotherapy in breast cancer (author's transl)].

The results are presented of postoperative irradiation in the treatment of breast cancer at the Department of Radiotherapy and Radiobiology, University of Vienna. Our data compare well with the best results reported in the literature. Apart from the importance of high loco-regional freedom from disease for the quality of life of these patients, the related increase in survival prospects is stressed.

Breast Neoplasms↗

[Computer tomography in therapy planning (author's transl)].

A report is given on the utilization of computer tomography for the irradiation planning. Owing to international cooperation it was possible to use the obtained pictures as a basis for a computerized irradiation planning. The authors give some practical examples of optimized isodose plans for individual cases which have been elaborated by using the computer-tomographic cross-section pictures and the computerized system for irradiation planning and which give a good idea of the efficiency of the system.

Decision Making↗

[Rare case of an adult teratoma of the stomach (author's transl)].

The teratoma is a dysgenetic tumor consisting of tridermal differentiation products. The most common classification is made according to maturity - benign adult teratoma and malign nonmature embryonal teratoma. In the case demonstrated, a 15-year-old male suffers from tiredness, paleness and pains in the epigastrium. The radiological examination showed a tumor in the size of a fist with a number of teeth located partly within the stomach. The histological findings after operation confirmed the diagnosis of a coetaneous (= adult) gastric teratoma. The discussion shows that all cases of gastric teratoma published until 1972 are male, in 77% under the age of 1 year, in 13% under the age of 10, and only in 10% over the age of 10 years.

Adolescent↗

Clinical outcome of salmon calcitonin nasal spray treatment in postmenopausal women after total hip arthroplasty.

OBJECTIVE: The increasing rate of hip fractures is giving rise to a number of socio-economic problems for the aging community. In addition to being unable to resume their previous living habits, many patients fail to achieve full functional recovery after the fractures. Total hip arthroplasty (THA) is a successful operation for the majority of patients with all forms of hip fractures, being performed increasingly often throughout the world. Revision rates for THA range up to 20% per year. Aseptic loosening is the reason for 75% of the revisions. An additional problem post-THA is the rate of heterotopic soft tissue calcification after THA, resulting in severely impaired function, pain, and a reduced range of hip movement. SUBJECTS: In an open study, 37 women who had undergone cementless THA after accidental hip fractures were treated twice daily with 200 IU of salmon calcitonin nasal spray for 12 months. Simultaneously the patients received one bag of 1,000 mg calcium plus 880 IU vitamin D daily throughout the treatment period of 1 year. A parallel group of 38 women with a similar clinical status in terms of hip fractures and cementless THA were treated with only one bag of 1,000 mg calcium plus 880 IU vitamin D daily through the treatment period. RESULTS: The results of this 12-month clinical trial show that 200 IU of salmon calcitonin nasal spray per day significantly improves the clinical outcome of postmenopausal elderly women following THA. Treatment with a salmon calcitonin nasal spray significantly reduces bone turnover, loss of bone density, and pain. The functional status of the patients was improved and the risk of falling reduced by rehabilitation during the observation period of 12 months. Additionally, calcitonin promoted the repair of hip fractures and was associated with a significantly lesser rate of refractures as well as periprosthetic ossifications. CONCLUSION: The increasing revision rate for THA during the first year and the patient's problem of resuming their previous living habits are the main foci of our study. Calcitonin nasal spray seems to cause few side effects. The additive treatment appears to improve the clinical outcome of THA in elderly postmenopausal women.

Administration, Intranasal↗