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Biomedical subjects

W McLean

Publications and source records attributed to W McLean.

3 recordsLinked to original sources

An epilepsy workshop for professionals.

This experimental study evaluated the impact of an epilepsy workshop format designed for community professionals who may be involved in the treatment plan and follow-up of patients. The goals of the workshop were to increase the professional's knowledge and comfort in the presence of epilepsy and to effect better delivery of services to patients. To achieve this, a didactic approach to learning was modified to include patient contact and participant involvement in the learning process. A pre- and posttest experimental design was utilized. Those who attended the workshop improved significantly more than the two control groups in their knowledge of and comfort with epilepsy. Following the workshop, there was a marked increase in the referral of school children for possible neurological problems by teachers who had attended. There was a subsequent improvement in the delivery of health care services to such children in this county.

Adolescent

Secretion and role of androgen-binding proteins in the testis and epididymis.

The Sertoli cell appears to be a target cell for both FSH and androgen. FSH stimulates the Sertoli cell to produce an androgen-binding protein (ABP) which may serve to increase the accumulation of androgen in the seminiferous tubular epithelium and make it available for binding by intracellular androgen receptors. This might be one way by which FSH enhances the action of androgen on spermatogenesis. Androgen acts on the Sertoli cell to increase its response to FSH resulting in increased production of ABP and of other substances which exert trophic effects on spermatogenesis.

Androgens

New systems for a two-speed electroencephalograph with an auditory device for diminishing the length of seizures.

The author describes a system for testing patients with petit mal seizures. The system has the following advantages: 1) EEG paper speed is automatically increased from 2.5 mm/s to 25 mm/s when brainwave activity increases, with the increased speed maintainable for up to 4.0 sec after the last seizure burst. Control studies with constant speed and two-speed systems operating simultaneously demonstrate that no significant distortion occurs at the moment of change in speed. The convenience of handling a greatly reduced volume of paper is obvious. 2) An auditory stimulus, either a pure tone burst of 1000 HZ or loud music, is also triggered by an increase in amplitude of brainwave activity. Testing of 15 patients shows a significant decrease (p less than 0.01) in duration of seizure activity when the stimulus is activated.

Acoustic Stimulation