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Biomedical subjects

W Meister

Publications and source records attributed to W Meister.

At least 73 records · Page 4Linked to original sources

[Contribution to the assessment of physical fitness in patients with pulmonary diseases on the basis of cardiopulmonary and ergometric parameters (author's transl)].

In 270 patients with COLD, bronchial asthma, exogenic allergic alveolitis or fibrosis of the lung measurements of VC, FEV 1,0, Rt, RV, DL CO, CL, PO2 and PAP (by means of floating catheter) were made. Results of measurements at rest and during exercise were compared after statistical treatment in the above groups and their value with regard to the determination of physical fitness was appreciated.

Adolescent↗

Long-term digitalis therapy improves left ventricular function in heart failure.

To clarify the controversy regarding the benefits of long-term oral digoxin in the treatment of heart failure, we evaluated hemodynamics at rest and during exercise in nine patients in sinus rhythm with symptomatic heart failure. Patients were studied during long-term digoxin therapy, after withdrawal of the drug, and six hours after readministration. Upon withdrawal of digoxin, pulmonary capillary-wedge pressure increased from 21 +/- 8 to 29 +/- 10 mm Hg, and cardiac index decreased from 2.4 +/- 0.7 to 2.1 +/- 0.6 liters per minute per square meter of body-surface area, suggesting a deterioration in left ventricular function. In addition, heart rate tended to increase and stroke-work index, stroke-volume index, and radioangiographic ejection fraction decreased. Acute readministration restored the hemodynamic values to those observed during long-term digoxin therapy. The improvement in hemodynamics during long-term digoxin administration was also observed during exercise. This improvement demonstrated the value of long-term oral digoxin therapy in congestive heart failure.

Administration, Oral↗

[Suggestions for diagnosis and differential diagnosis of bronchial asthma (author's transl)].

The diagnosis of bronchial asthma is difficult because dyspnea as the leading symptom is ambiguous. Often other diseases with dyspnea are called asthma. For long term treatment it is necessary to know the pathogenesis of asthma and the factors triggering attacks. This in many cases needs special investigations. In the present paper some proposals are given to make a preliminary diagnosis on the basis of history and simple clinical findings, giving the indication for consecutive investigations respectively referring the patient to a specialist.

Allergens↗

[The assessment of invalidity in chronic bronchitis (author's transl)].

There are no fixed rules for the assessment of invalidity in chronic bronchitis and its complications. The methods of examination and the interpretation of the results are very different. The main cause of invalidity is diminished cardiopulmonary function. Therefore, lung function tests are of great importance. But some other important aspects have to be considered too, f.e. concomitant diseases, age and profession, possibilities to arrange a suitable place of employment, results of treatment. In this paper are discussed proposals for a complex assessment of invalidity including social and psychological aspects.

Adult↗

[The department for bronchial asthma in the chest hospital (author's transl)].

The regression in morbidity of tuberculosis has changed the profile of the chest hospital. The number of patients with chronic obstructive lung diseases increased considerably. Special efforts are necessary for their diagnosis, therapy and assessment. Therefore it is favourable to concentrate patients with bronchial asthma in special departments and to qualify the medical staff in these special problems. In this paper a report is given on our own experience with such a special department for bronchial asthma in the last eight years.

Asthma↗

[Suggestions for health education in a chest hospital (author's transl)].

Health education is of great importance in therapy and rehabilitation of patients with chronic obstructive lung diseases. A healthy manner of living has great influence on the success and effectivity of therapy and rehabilitation. In this paper a report is given on the systematic integration of health education in the daily work of a great chest hospital, especially regarding the main topics of health education in lung diseases and the specific methodic possibilities in a hospital as well as the systematic integration in the management and the self-improvement of the medical staff.

Education, Continuing↗

[Various forms of drug-induced pulmonary eosinophilia].

On the basis of 3 casuistics the in most cases medicamentous allergic etiology of chronic eosinophilic lung infiltrates, their diagnosis and differential diagnosis is discussed. Practical conclusions to the possibly early recognition of eosinophilic infiltrates, the prevention of therapeutic errors and the severe courses of disease resulting from this are reported.

Adult↗

[Rehabilitation of chronic obstructive pulmonary diseases at the lung hospital (author's transl)].

The modern lung hospital offers favorable conditions for the rehabilitation of patients suffering from chronic obstructive pulmonary diseases. In the years from 1972 to 1976 2398 patients suffering from chronic bronchitis, bronchial asthma and pulmonary emphysema were subjected to a rehabilitation process at the central hospital for heart and lung diseases Bad Berka. A long-term therapy plan based on a most accurate investigation possible of all the factors which trigger off the complaint in each case was used as baseline. An account is given of the resulting diagnostic and therapeutic program carried out. In the case of chronic obstructive pulmonary diseases it is particularly difficult to assess the effectiveness of rehabilitation measures. One aspect dealt with is the restoration of working capacity. 56.7% of the men and 56.8% of the women were capable of working when they were dismissed. 31.6% of male and 26.4% of female patients were invalids, 11.7% and 16.8% respectively were old age pensioners. Rehabilitation success depended on variables such as age, degree of cardio-pulmonary limitation in performance, as well as on certain concomitant diseases and the patient's cooperation. A decisive factor in some cases was also whether suitable employment could be found for these patients whose age ranges between 40 and 60.

Adult↗

[Venous thrombosis during long-term corticoid therapy in chronic obstructive lung diseases].

Venous thrombosis is a serious disease. In the case of chronic obstructive lung diseases several causes of venous thrombosis coincide being polycythemia, thrombocythemia the patient's limitation of exercise and the low flow rate of the venous blood. The therapeutic administration of corticoids leads to polycythemia and thrombocythemia. The high risk of venous thrombosis must be always regarded in corticosteroid therapy of chronic obstructive lung disease. Preventive measures should be provided.

Adult↗

[Diagnosis and therapy of hay fever in the clinic for lung diseases and tuberculosis].

In general the special diagnostics and therapy of hay-fever are done by the otorhinolaryngologist. Recently patients are often referred to the Chest Clinic for allergologic diagnostics and for classification of bronchial asthma simultaneously existing. The specialist in the Chest Clinic must be experienced also in the problems of allergic rhinitis, at least in a sufficient extent. Therefore, practical proposals for diagnostics, differential diagnosis and therapy of allergic rhinitis and especially of hay-fever are given in this paper considering recent literature and own experience in an allergologic consulting cabinet.

Adrenal Cortex Hormones↗

Carotenoids of rhizobia. II. The effect of nicotine on the carotenoid pattern of Rhizobium lupini.

With increasing concentrations in the growth medium of the cyclization inhibitors nicotine or 2-(4-chlorophenylthio)-triethylamine hydrochloride (CPTA) the previously identified bicyclic carotenoids of Rhizobium lupini (2,3,2',3'-tetrahydroxy-beta,beta-caroten-4-one and 2,3,2',3'-tetrahydroxy-beta,beta-carotene) were successively replaced by hitherto unknown monocyclic carotenoids. By application of mass and nuclear magnetic resonance spectroscopy 3 carotenoids were identified as 2,3-trans-dihydroxy-beta,psi-caroten-4-one, 2,3-trans-dihydroxy-beta,psi-carotene, and 3-hydroxy-beta,psi-caroten-4-one. A further compound was tentatively established as (2- or 3-)monohydroxy-beta,psi-carotene. It was found that other inhibitors such as diphenylamine or 4-chloro-5-(dimethylamino)-2-alpha,alpha,alpha(trifluoro-m-tolyl)-3-(2H)-pyridazinone (San 6706) did not affect the pigment pattern. The results are discussed in relation to carotenoid biosynthesis in Rhizobium lupini.

Carotenoids↗