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Biomedical subjects

W R Harrison

Publications and source records attributed to W R Harrison.

41 records · Page 3Linked to original sources
PubMed1985

Irrational ideas. Older vs. younger inpatients.

The relationship to age of irrational beliefs among psychiatric inpatients has not been explored using the rational-emotive model. This study addressed the following two questions: 1) Do older and younger psychiatric inpatients differ in irrational beliefs? 2) Do older depressives differ from older nondepressives in irrational beliefs? Upon admission to a large medical center, 58 younger (less than 45 years old) and 54 older (greater than 55 years old) subjects were assessed on a battery of psychological tests, including the Idea Inventory and the Beck Depression Inventory. Results showed that older and younger inpatients did not differ on irrational beliefs. Results also showed that older and younger groups of depressives did not differ on the irrationality scores. When a correlational analysis was used, depression was related to irrationality within the older group but not within the younger group.

Adult↗
PubMed1984

Older alcoholics: profile of decline.

Administered to 235 chronic alcoholics in an inpatient setting a standard psychological test battery 2 weeks after admission. Two analyses were calculated: A correlational analysis between age and the test variables and a comparison analysis between a younger (less than 50) and an older group. Results suggest that visual-spatial and constructional tasks, newer learning tasks, and secondary memory (and memory delay) show a more pronounced decline than do verbal or "left hemisphere" tasks. A sub-analysis of 30 younger and 30 older psychiatric patients further revealed that alcohol asserts a significant influence on decline in complex abstract tasks and on visual-spatial tasks (age is also a significant factor on visual-spatial tasks). This study re-validated previous findings using a more chronic alcohol population with standard psychological tests in a clinical setting.

Age Factors↗
PubMedDate not supplied

Multifocal osteosarcoma: an unusual presentation.

PURPOSE: Report the unusual presentation, clinical course, and cytogenetic abnormalities in a child with multifocal osteosarcoma. PATIENTS AND METHODS: A 10-year-old boy had multifocal osteosarcoma involving the entire skeleton, pleura, bone marrow, and lungs. He had marked anemia, thrombocytopenia, and severe hypocalcemia at diagnosis. RESULTS: Despite aggressive chemotherapy, he died from progressive disease 1 month after diagnosis. Cytogenetic analysis of tumor cells within the pleural fluid showed multiple chromosomal abnormalities with amplification of the c-myc oncogene. CONCLUSION: Multifocal osteosarcoma should be considered in the differential diagnosis of a child with pancytopenia and multiple bone lesions. Amplification of the c-myc oncogene may have had a significant role in the pathogenesis, etiology, and rapid progression of this patient's multifocal disease. Additional studies will be needed to determine the biologic significance of c-myc amplification in multifocal osteosarcoma.

Child↗
PubMedDate not supplied

Painless myocardial infarction with interventricular septal rupture presenting as the acute onset of congestive heart failure.

Two cases of ventricular septal rupture complicating infero-posterior myocardial infarction which are atypical in presentation, clinical course, and outcome are presented and the relevant literature is reviewed. The patients presented late after the acute onset of congestive heart failure, without a history of chest pain, were diagnosed noninvasively, survived with medical therapy for 2 and 4 months, and went on to successful surgical repair.

Aged↗