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Biomedical subjects

W Rösch

Publications and source records attributed to W Rösch.

At least 163 records · Page 9Linked to original sources

[The association of ulcer and cancer is no rarity].

Out of 100 patients with early gastric carcinoma 4 cases with a combined benign gastric and/or duodenal ulcer were encountered. Even in long-lasting peptic ulcer history and multiple benign biopsies carcinoma may develop at some site in the ulcer stomach. That's why intermittent therapy based on ulcer symptoms in a patient with chronic ulcer disease remains problematic. Carcinoma incidence seems to be identical in patients with gastric and duodenal ulcer and does not differ from a population with an ulcer-free stomach.

Adenocarcinoma↗

[Changes in gastroenterology by endoscopy. Diagnostic and therapeutic progress in gastric carcinoma (author's transl)].

Since the introduction of routine fiberendoscopy of the upper alimentary tract, for the majority of the patients as primary diagnostic method, the number of early gastric carcinomas has significantly risen. Differentiation between benign and malignant lesions is nowadays possible with an accuracy of 99,8%. Endoscopic determination of tumour invasion is limited. Of utmost importance is the differentiation between intestinal and diffuse type carcinoma. Ulcer carcinomas as malignant degeneration of chronic callous ulcers are an extreme rarity. Of special significance is the endoscopic follow-up of patients resected because of gastric carcinoma since only by routine biopsy from the anastomosis early, recurrency may be detected.

Adult↗

[Oesophageal disorders: a gastroenterologist's view].

For precise differentiation between organic and functional disorders of the oesophagus, the gastroenterologist makes use of radiology, endoscopy, and manometry, although a questionnaire may establish the final diagnosis in dysphagia with 95% accuracy. Combined therapy is gaining in increasing importance, such as dilatation of achalasia, bouginage of peptic strictures, implantation of prostheses and sclerosing of varices during endoscopy. For early diagnosis of carcinoma, close interdisciplinary cooperation between the ENT-specialist and the gastroenterologist is mandatory in panendoscopy of the squamous epithelium-lined aero-digestive system.

Adenocarcinoma↗

[Causes of death following endoscopic papillotomy].

The results of autopsy carried out in 14 patients who died after undergoing papillotomy show that apart from non-method-related sepsis (4 cases) developing from a cholangitis in underlying choledocholithiasis, haemorrhage from the papillotomy wound is the most dangerous complication of this intervention. In one case the cause of bleeding was the severance of the retroduodenal artery, while in 3 cases bleeding occurred after a repapillotomy. In these patients the source of bleeding was a highly vascular granulation tissue in the early healing phase after the first papillotomy. In view of this danger, the primary papillotomy should as far as possible be a complete one, or else, no repapillotomy should be performed in the proliferation phase of wound healing.

Adult↗

[Anastomotic ulcer following Whipple's operation with stomach preservation].

Using the method proposed by Traverso and Longmire, a partial duodenopancreatectomy was performed on 18 patients without concomitant gastric resection sparing the bulbus duodeni. It had been reported that the postoperative increase in ulcer formation on the anastomosis could be avoided by a duodenal inhibition of gastric secretion. Since, however, ulcers were found in 7 patients on an average of 13 months following surgery, it must be presumed that the duodenal acid inhibition is not sufficient. For this reason Whipple's operation is again being performed in combination with the subtotal gastric resection.

Adult↗

A special form of segmental pancreatitis: "groove pancreatitis".

"Groove pancreatitis" is a form of segmental pancreatitis affecting the head of the pancreas which is localized within the "groove" between the head of the organ, the duodenum and the common bile duct. We diagnosed this form of pancreatitis in 30 out of 123 surgical duodenopancreatectomy specimens of chronic pancreatitis (24.4%). In a comparison with non-segmental chronic pancreatitis, no differences was observed in age and sex distribution or in alcohol consumption. Clinically, in contrast, preceding diseases of the biliary system, peptic ulcers and gastric resections were more frequently indicated. The cardinal clinical finding is frequently duodenal stenosis; in sonographic and CT examinations, the cicatricial "plate" in the "groove" represents as a "tumor", so that--also on account of the frequent duodenal stenosis--a carcinoma of the head of the pancreas may be suspected. In groove pancreatitis, the pancreatic duct system is grossly normal, calcifications or intraductal protein plugs being rare and an adaptive intimal fibrosis of the intrapancreatic arteries and arterioles is found only within the cicatricial area. Very commonly, scarring of the duodenal wall, stenosis of the duodenum, true duodenal wall and pancreatic cysts are detected. Aetiopathogenetic possibilities are previous diseases of the biliary system, peptic ulcers, gastric resections, true duodenal wall cysts, pancreatic head cysts, pancreatitis in duodenal pancreatic heterotopia, and disturbances of pancreatic juice outflow in Santorini's duct in the absence of the minor papilla, and hyperstimulation in consequence of chronic alcoholism.

Adult↗

[Sonographic measurement of gastric emptying time].

Sonography, as a non-invasive procedure, may be used also for studying the gastric emptying time. After 250 ml of a liquid test meal the gastric emptying time was determined in 20 subjects. In each subject the applied test meal could be traced in the prepyloric antrum. When examined at 8.00 a.m. the fluid had left the stomach after an average time of 8.3 min. During the day the emptying time increased to 10.8 min. A second examination on another day after application of 30 mg metoclopramide revealed significantly lower gastric emptying time. Ultrasonography may therefore be used as a sensitive non-invasive method for studying the gastric emptying rate in the fasting state and under pharmacological stimulation.

Gastric Emptying↗

[Ultrasound measurement of gastric emptying time values].

Sonography, as a non-invasive procedure, may be used also for studying the gastric emptying time. After 250 ml of a liquid test meal the gastric emptying time was determined in 20 subjects. In each subject the applied test meal could be traced in the prepyloric antrum. When examined at 8.00 a.m. the fluid had left the stomach after an average time of 8.3 min. During the day the emptying time increased to 10.8 min. A second examination on another day after application of 30 mg metoclopramide revealed significantly lower gastric emptying time. Ultrasonography may therefore be used as a sensitive non-invasive method for studying the gastric emptying rate in the fasting state and under pharmacological stimulation.

Antiemetics↗

[Gastrointestinal hemorrhage--angiodysplasia].

Clinico-pathological conference on the clinical picture of angiodysplasia--a rare source of bleeding in the upper gastrointestinal tract. In patients with relevant hemorrhagic symptomatology (tarry stools, anemia, possibly hemorrhagic shock), the diagnosis is established with the aid of angiography and endoscopy. Treatment consists in the resection of the section of bowel involved.

Aged↗

[Chronic pancreatitis and the neighboring organs].

The close topographic relationship between pancreas and the functional entity of the upper abdominal organs causes in about 20 percent of the patients with chronic pancreatitis alterations of the surroundings. In 531 patients compression of the common bile duct was found in 18.1%, duodenal stenosis in 17.7%, pleural thickening in 6.6%, splenic vein thrombosis in 5.1%, gastric outlet obstruction in 3.2% and colonic stenosis in 0.4%. In primary asymptomatic chronic pancreatitis these local complications may be the first hint to pancreatic disorders. Occasionally these changes demand operative interventions or alleviate the decision for resectional therapy.

Adult↗

[Diagnosis of the irritable colon: manometric and myoelectric investigations (author's transl)].

Manometric investigations of patients with irritable colon show an undisturbed cyclic course of interdigestive motility studies of the rectosigmoid in patients with irritable colon show a spectrum of variable frequency of slow membrane potential changes with predominance of a frequency of 3/min. In addition, after a 1000 calorie test meal, patients with irritable colon showed a significantly prolonged increase of motility. As functional disturbances of irritable colon are mainly diagnosed by exclusion of organic changes, further development and rational use of colonic myoelectric methods promises future possibilities for objective diagnosis and control of treatment.

Adult↗

[Spectrum of esophagitis: etiology, diagnosis, therapy].

Inflammatory changes of the oesophageal mucosa are in the vast majority due to reflux of gastric content. Caustic oesophagitis is rare, however, drug-induced oesophageal injury caused by delayed passage is of increasing importance. Infections by opportunistic saprophytes (candida, herpes virus) are common causes of oesophagitis in immunocompromised patients with dysphagia and odynophagia whereas specific inflammation (Crohn's disease, tuberculosis) is a rarity. Successful therapy demands precise differentiation of the different forms of oesophagitis.

Calcium Chloride↗