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Biomedical subjects

W Rösch

Publications and source records attributed to W Rösch.

At least 181 records · Page 10Linked to original sources
PubMed1981

[Biliary excretion of mezlocillin].

2 g of mezlocillin were given at different time intervals (1/4, 1/2, 1, 2, 4, 10, 14, 18 hours) to patients in whom endoscopic retrograde cholangiography (ERC) was scheduled for antibiotic prophylaxis. Prior to the instillation of the contrast medium 5 ml of bile were aspirated and the concentration of the antibiotic determined via agar diffusion in comparison to the serum level. Serum levels reached a peak of 105 micrograms/ml whereas bile levels reached a mean level of 4000 micrograms/ml. In patients with intact liver function mezlocillin is concentrated to a factor of 40 within bile. Complete elimination in serum occurs after 4 to 5 hours, in bile after 18 to 24 hours.

Bile↗
PubMed1981

Biological and biochemical analysis of endoscopically aspirated bile.

Selective cannulation and aspiration of bile prior to ERCP may be helpful in bacterial contamination (suppurative cholangitis), in patients with choledocholithiasis, to determine lithogenicity of bile, and in studies where antibiotic concentration of different substances are analyzed in correlation to hepato-biliary diseases. Results of appropriate examinations are presented.

Ampulla of Vater↗
PubMed1981

Long-term follow-up after endoscopic sphincterotomy.

Endoscopic sphincterotomy has become a well-accepted procedure in choledocholithiasis and papillary stenosis. Long-term follow-up data covering an observation period of 7 years disclose that about 90% of the patients are either completely relieved of symptoms, or show marked improvement. Re-stenosis or recurrent concrements seem are events; in primary papillary stenosis, however, long-term results are less favorable.

Ampulla of Vater↗
PubMed1981

Non-surgical biliary drainage - technique, indications and results.

Nonsurgical biliary drainage offers a therapeutic alternative in the palliation of malignant obstructive jaundice. Two basic approaches are available. The percutaneous transhepatic method can be employed either for external drainage or for the placement of an internal endoprosthesis. In the case of the transduodenal, transpapillary approach, either a pigtail catheter can be placed, after prior papillotomy, or - with or without the need to split the papillar - a nasobiliary drainage tube can be introduced. Successful drainage was achieved in 67 patients. In the majority of cases, external drainage was performed as a palliative measure in inoperable carcinoma of the biliodigestive system. In addition, however, pre-operative temporary drainage was also carried out to reduce the risks of surgery in patients with severe obstructive jaundice. The complication rate was low. Apart from biliary peritonitis, cholangitis and minor bleeds were observed. The rate of failure for technical reasons was a relatively low 10%.

Bile Duct Neoplasms↗
PubMed1981

Tuberculosis of the pancreas.

In a case report, the rate condition of tuberculosis of the pancreas is described. There are two conceivable ways in which the pancreas may become diseased: 1. toxic-allergic reaction of the pancreas in response to generalized tuberculosis (so-called concomitant pancreatis) 2. Invasion of the pancreas by tubercle bacteria disseminated via the blood, or through penetration of the organ by adjacent caseating abdominal lymph nodes. Histologically, epithelioid cells and Langhans' giant cells are only rarely found; caseation usually develops, with subsequent calcification, which can lead to stenosis of the pancreatic duct. In patients with generalized tuberculosis and abdominal complaints, the diagnosis is most reliably established on the basis of ERCP and CAT. In the presence of pain, resection of the affected portion of the pancreas may be considered as means of treatment.

Cholangiopancreatography, Endoscopic Retrograde↗
PubMed1981

[Early gastric cancer--special geriatric problems (author's transl)].

With increasing age polypous growth predominates among early gastric cancers. These polypoid carcinomas corresponding to intestinal type carcinoma are seen together with chronic atrophic gastritis, in part they originate from precancerous conditions like adenoma or borderline lesion. Our experience in 86 patients with early gastric carcinomas shows that associated lesions like hyperplasiogenic polyps (17.4%), adenoma and borderline lesion (8.1%) and synchronous carcinoma (9.3%) are common. 5-year-survival rate corresponds with a figure between 70 and 100% according to the histological type and depth of infiltration with the Japanese literature. In geriatric patients therapy should be individually adopted. Local measures like surgical excision or endoscopic polypectomy may be used alternatively to classical surgery.

Adenoma↗
PubMed1980

[Irrigation treatment of concrements in the common bile duct with octanoate (Capmul 8210) (author's transl)].

An irrigation treatment using the octanoate mixture Capmul 8210 of a maximum duration of 10 days was performed in 11 patients with concrements in the common bile duct using either a T-drain (n = 6) or a permanent naso-biliary tube (n = 5). In 6 out of the 11 cases total or partial dissolution led to voiding of concrements without further operative or invasive procedures. The treatment was tolerated in all but two cases. There was no evidence of systemic toxic side effects. Local inflammatory mucous membrane damage due to the instillation was observed in two cases.

Adult↗
PubMed1980

[Stimulation of esophageal motility with bromoprid, domperidon and metoclopramide. Therapy of esophageal reflux disease].

This double-blind and cross-over study was designed to compare the effect of domperidon, metoclopramide and bromopride on esophageal motility. A stimulating effect on lower esophageal sphincter pressure (LESP) was shown after i.v. bolus of all three substances, not after saline (control period). LESP was rised significantly up to 50 min above basal levels. Motility pattern of the esophagus was also stimulated up to 50 min.

Adult↗
PubMed1980

Endoscopic lithotripsy in the common bile duct.

Electrohydraulic lithotripsy of stones lodged in the common bile ducts of human patients has been successfully accomplished. For this purpose, the lithotripsy probe was integrated with a Dormia basket. Common duct stones not otherwise amenable to release by endoscopic papillotomy can be removed by this procedure. A prerequisite, however, is that the stone to be shattered must be firmly lodged within the Dormia basket.

Endoscopes↗