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Y Atomi

Publications and source records attributed to Y Atomi.

At least 127 records · Page 7Linked to original sources
PubMed1985

[Pathophysiology and prognosis of acute pancreatitis--early and late prognostic signs].

The purpose of this study is to elucidate the pathophysiology of the acute pancreatitis and set up the criteria for assessing the severity of this disease. One hundred and fifty seven cases of acute pancreatitis were treated at the First Surgical Department of Tokyo University Hospital and its affiliated hospitals. They consisted of 24 severe cases, 76 moderate cases, and 57 mild cases according to our classification. In early stage ten parameters, namely, abnormalities of white cell count, platelet count, hematocrit, lactic acid dehydrogenase, blood urea nitrogen, serum calcium, base excess, PaCO2 and fasting blood glucose and age within 24 hours after admission and X-ray CT scan within 48 hours as early prognostic signs, enabled us to predict severe, moderate, or mild pancreatitis. More than 4 weeks later than the onset of acute pancreatitis, X-ray CT scan, white blood cell count, elevation of serum FDP level, endotoxemia and fall of plasma opsonic index served as good indicators to evaluate the severity of abdominal sepsis. In experimental pancreatitis, CH50 and opsonic index were remarkably decreased at 6 and 12 hours after induction of acute pancreatitis. As the above results, determination of early prognostic signs immediately after onset and late prognostic signs 3-4 weeks after onset is very important to evaluate and manage the acute pancreatitis patients.

Acute Disease↗
PubMed1984

Blood glucose concentration dependent ACTH and cortisol responses to prolonged exercise.

The purpose of this study is to investigate responses of serum ACTH and cortisol concentration to low intensity prolonged exercise. In experiment 1, 10 subjects fasted for 12 h and performed bicycle exercise at 49.3% VO2max (+/- 4.3%) until exhaustion or up to 3 h. During the early part of the exercise, serum ACTH and cortisol concentrations did not increase from the pre-exercise values (ACTH: 44 +/- 5 micrograms/l, cortisol: 139 +/- 52 micrograms/l). Whilst the time to serum ACTH concentration increasing varied among the subjects (60-180 min), the increases of this hormone occurred for all subjects (175 +/- 85 ng/l, P less than 0.05) when blood glucose concentration decreased to a critical level of 3.3 mmol/l. At the end of the exercise, blood glucose concentration decreased to 2.60 +/- 0.21 mmol/l, and serum ACTH and cortisol concentrations increased to 313 +/- 159 ng/l and 371 +/- 151 micrograms/l, respectively. In experiment 2, four subjects performed the same intensity exercise until exhaustion, and were then given 600 ml of 20 g glucose solution, and immediately afterwards, they were asked to repeat the same exercise. The subjects continued the exercise for between 30 to 90 min until again reaching exhaustion. During the second exercise, blood glucose concentration increased to the pre-exercise value (2.72 +/- 0.58 to 4.00 +/- 0.22 mmol/l, P less than 0.05) and simultaneously, serum ACTH concentration decreased considerably (354 +/- 22 to 119 +/- 54 ng/l, P less than 0.05). The results of the present study suggest that serum ACTH and cortisol concentration during low intensity prolonged exercise may be dependent on blood glucose concentration.

Adrenocorticotropic Hormone↗
PubMed1984

Enhancing effect of bile and bile acid on stomach tumorigenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.

The carcinogenic or cocarcinogenic effects of bile or bile acid on stomach carcinogenesis were investigated in inbred W rats. Bile or bile acid was introduced into the stomach by choledochogastrostomy or with food after the administration of N-methyl-N'-nitro-N-nitrosoguanidine [(MNNG) CAS: 70-25-7; 1-methyl-3-nitro-1-nitrosoguanidine] in drinking water. The animals that received MNNG and bile or sodium taurocholate (CAS: 145-42-6; N-choloyltaurine sodium salt) had a significantly higher incidence of hyperplastic and neoplastic lesions in the stomach mucosa than did the relevant MNNG-treated controls. The result suggested an enhancing effect of bile and sodium taurocholate in stomach tumorigenesis.

Animals↗
PubMed1983

Computed tomography and sonography of cavernous hemangioma of the liver.

Accuracy and limitations of computed tomography (CT) and sonography in the detection and diagnosis of cavernous hemangioma of the liver were analyzed in 39 cases. In 35 of 38 lesions examined by CT before and after bolus contrast enhancement, findings were dense contrast enhancement spreading in all directions on subsequent scans and/or density (other than capsule or septa) higher than normal hepatic parenchyma after 2 min. Lesions smaller than 1 cm were not detected. Misregistration in sequential scans prevented diagnosis of three of nine lesions smaller than 2 cm. Sonography revealed various patterns of mass, but in the smaller lesions, an extremely hyperechoic pattern was dominant. The contributions of CT and sonography depend on the size of the lesions.

Adult↗
PubMed1980

Effect of training intensity in adult females.

The aim of this study was to investigate the effect of training intensity on maximal aerobic power on the basis of the subjects lean body mass. Seven sedentary adult females aged 23-40 years participated in a 44-week training experiment. They trained on a bicycle ergometer at progressive intensities of 60, 75, and 90% VO2 max for 13, 18, and 13 consecutive weeks, respectively. The total amount of work was between 9,000 and 12,000 kpm a day and frequency between 2 and 4 days a week, keeping both factors approximately constant for each subject throughout the 44-week training period. Mean VO2 max increased significantly during 60 and 90% VO2 max training. The increase during 75% VO2 max training was not significant. The final values during the three training periods were not necessarily the highest ones. Keeping the effect of age statistically constant, a significant partial correlation developed between the initial values and the total gains (%) of VO2 max, VE, and O2 pulse, expressed per lean body mass (LBM). The final attained values of VO2 max per LBM were significantly correlated with age. Therefore, if training intensity is sufficiently effective, it might be assumed that everyone has the same capacity for the improvement of cardiorespiratory function corresponding to their lean body mass, which is related to the magnitude of muscle mass. Furthermore, it might be said that the attainable level of aerobic power is greatly limited by the effects of age.

Adipose Tissue↗
PubMed1980

Computed tomography and ultrasound in the diagnosis of intrahepatic calculi.

Computed tomography (CT) and ultrasound were used to evaluate intrahepatic biliary calculi in 16 patients. Thirteen demonstrated high-density shadows in dilated intrahepatic ducts on CT. Of the 11 who also underwent ultrasonography, 7 had positive findings. Strong echoes with acoustic shadows in dilated intrahepatic biliary ducts are diagnostic of stones. CT and ultrasound are useful in evaluating intrahepatic calculi, with CT being particularly helpful in postoperative cases.

Adult↗
PubMedDate not supplied

Anomalous pancreaticobiliary junction demonstrated by extraductal ultrasonography using transduodenoscopic miniprobe.

We present a case of an anomalous pancreaticobiliary junction (a long common channel) that was clearly demonstrated by extraductal ultrasonography with a transduodenoscopic miniprobe placed in the duodenal lumen. The present case suggests a potential indication for the ultrasound miniprobe, in extraductal ultrasonography, in the pancreatobiliary region. In this method, the position of a miniprobe can readily be adjusted under endoscopic guidance, unlike ordinary endoscopic ultrasonography.

Aged↗
PubMedDate not supplied

Diagnosis of portal venous invasion by pancreatobiliary carcinoma: value of endoscopic ultrasonography.

BACKGROUND: We evaluated the usefulness of endoscopic ultrasonography for detecting pancreatobiliary carcinoma and assessing portal venous invasion by carcinoma. METHODS: Seventy-three patients with pancreatic carcinoma (54 patients) or bile duct carcinoma (19 patients) underwent endoscopic ultrasonography, transabdominal ultrasonography, computed tomography (CT), and angiography. All patients underwent tumor resection and histological examination for portal venous invasion. Results of endoscopic ultrasonography were compared with those of other imaging modalities. RESULTS: Histopathology revealed portal venous invasion in 20 patients. Endoscopic ultrasonography was significantly more sensitive (96%) than ultrasonography (81%), CT (86%), and angiography (59%) in detecting carcinomas. On endoscopic ultrasonography, loss of the echogenic vessel-parenchymal sonographic interface or a tumor within the vessel lumen indicated portal venous invasion. For diagnosing portal venous invasion, endoscopic ultrasonography was more sensitive (95%) and accurate (93%) than ultrasonography (55% and 67%), CT (65% and 74%), and angiography (75% and 79%), respectively. CONCLUSION: Endoscopic ultrasonography is the most accurate tool for detecting pancreatobiliary carcinomas and assessing portal venous invasion.

Adult↗
PubMedDate not supplied

CT demonstration of gas in dilated pancreatic duct.

A case of "innocent" pancreatic gas is reported. The patient had cystic dilatation of the main pancreatic duct limited to the head. Air entered through the patulous ampulla of Vater. Pancreatic gas can be present without abscess or fistula.

Aged↗
PubMedDate not supplied

Microcystic adenoma of the pancreas: spectrum of computed tomographic findings.

Fourteen cases of microcystic adenoma (serous cystadenoma) of the pancreas were reviewed and radiological findings were correlated with pathological specimens. Microcystic adenomas appeared grossly either as solid tumors with innumerable tiny cysts or as honeycombed cystic tumors depending on the size and number of cysts and amount of connective tissue. Dynamic enhanced CT of the tumor reflected the amount of connective tissue and appeared as (a) densely enhanced spongy masses (n = 6: classic appearance); (b) cystic masses with (n = 6) or without (n = 1) enhanced septa; or (c) dense diffusely enhanced mass (n = 1). Ultrasound similarly showed a variety of features such as echogenic masses with or without small cystic portions, multilocular cysts, or mixed hyperechoic and hypoechoic masses. The ultrasonic features mainly reflected the dominant sizes of cysts. Angiography almost always showed inhomogeneously hypervascular masses with tumor vessels. The imaging diagnosis is easy and conclusive in classic subtypes, but a correct diagnosis can be made even in other subtypes. However, mucinous cystic neoplasm can be confused with microcystic adenoma with large cysts and a small amount of connective tissue, and islet cell tumors can be mistaken for microcystic tumors with minute cysts.

Adult↗
PubMedDate not supplied

Endoscopic nasobiliary drainage for treating bile leak after laparoscopic cholecystectomy.

BACKGROUND/AIMS: Bile leaks are common complications of laparoscopic cholecystectomy. We evaluated the diagnosis and endoscopic treatment of bile leaks. METHODOLOGY: A total of 436 patients underwent laparoscopic cholecystectomy with infrahepatic drainage. We performed immediate endoscopic retrograde cholangiopancreatography (ERCP) on all patients with bile discharge from an infrahepatic drain, and treated bile leaks which were not due to a major ductal injury by endoscopic nasobiliary drainage (ENBD) without endoscopic sphincterotomy (ES). RESULTS: Ten patients developed bile leaks which were recognized within 18 hours of operation. ERCP, on post-operative day 1 or 2, showed a bile leak from the cystic duct (9 patients) or the liver bed (1 patient). All patients underwent ENBD. Only 1 patient, who had a retained stone, had ES. In all patients, the bile leak resolved promptly and both the infrahepatic and nasobiliary drains were removed within 6 days of cholecystectomy. All patients were asymptomatic at a mean follow-up of 30 months. CONCLUSIONS: Routine placement of an infrahepatic drain is recommended for the early detection of bile leaks. Bile leaks can be successfully treated by prompt ENBD without ES.

Adult↗
PubMedDate not supplied

Pancreatic metastasis from renal cell carcinoma causing massive gastrointestinal bleeding in von Hippel-Lindau disease.

Patients with von Hippel-Lindau disease (VHLD) may develop pancreatic lesions, including cysts, serous cystadenomas and islet cell tumors. However, only a few cases of pancreatic metastasis have been reported. We present a case of VHLD with multiple pancreatic metastases from renal cell carcinoma. One of the metastases invaded the duodenum, causing massive bleeding.

Carcinoma, Renal Cell↗