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Y Mito

Publications and source records attributed to Y Mito.

35 records · Page 2Linked to original sources
PubMed1980

Conversion of positive to negative chemotaxis by Ca2+ ionophore treatment in plasmodium of Physarum polycephalum.

The plasmodium of Physarum polycephalum was treated with Ca2+ ionophores A23187 or X-537A, and the effects on the chemotactic and contractile activities were studied by applying a double-chamber method and an optical method. (1) At low Ca2+ concentration, attractants (glucose, L-alanine) KH2PO4) remained as attractants and induced a relaxation in the plasmodial strand. Increase in the external Ca2+ level caused a contraction of plasmodium with the same stimuli, and hence converted the attractants to repellents. (2) This phenomenon was specific to Ca2+; Mg2+, Sr2+ or Ba2+ showed no appreciable effects. (3) Repellents (sucrose, KCl, Quinine) induced a contraction, which was not altered by the Ca2+ ionophore treatment. (4) Efflux of Ca2+, which was measured by chemiluminescence of aequorin, increased on glucose reception in the presence of ionophore.

Anti-Bacterial Agents↗
PubMed1980

Baroreflex sensitivity in renal failure.

1. Baroreflex sensitivity was evaluated in 22 non-dialysed patients with chronic renal failure secondary to chronic glomerulonephritis. Baroreflex sensitivity was judged by the slope of the linear regression of the pulse interval on the rise in systolic blood pressure with injection of phenylephrine or reduction by amyl nitrite inhalation. 2. Baroreflex sensitivity was reduced in these patients as compared with normal controls. Reduction of baroreflex sensitivity was significantly greater in nine hypertensive than 13 normotensive patients with chronic renal failure. 3. A significant positive correlation was found between baroreflex sensitivity and motor nerve conduction velocity measured on ulnar nerve in 13 patients examined. 4. Saline was given with high dietary salt intake to seven normotensive patients with chronic renal failure for 2 or 5 days in order to determine whether the severe depression of baroreflex sensitivity can be an initiating factor for hypertension. Blood pressure was raised to hypertensive levels within 5 days in two patients in whom baroreflex sensitivity was nearly as low as that of hypertensive patients, but not in five cases whose baroreflex sensitivity was normal or only mildly depressed. Plasma volume increased to the same degree in both groups. Baroreflex sensitivity did not change in the former two cases despite blood pressure elevation. 5. It is concluded that reduced baroreflex sensitivity in chronic renal failure correlated with the prescence ofhypertension, as well as uraemic neuropathy, and may be one of the pathogenetic mechanisms of hypertension in end-stage chronic glomerulonephritis.

Adult↗
PubMed1980

Selective suppression of positive chemotaxis in Physarum polycephalum by treatment with rotenone or under anaerobic condition.

The chemotactic motive force of plasmodia of Physarum polycephalum was measured by the double-chamber method. The treatment of plasmodia with 0.1 mM rotenone did not affect the motility of the palsmodia but led to suppression of the chemotaxis toward all the attractants examined (glucose, galactose, c-AMP, KH2PO4). Rotenone treatment did not affect the chemotaxis against repellents (fructose, NaCl). Similar results were obtained when the chemotactic motive force was measured under an anaerobic condition (95% N2-5% CO2).

Anaerobiosis↗