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Z Lević

Publications and source records attributed to Z Lević.

At least 37 records · Page 2Linked to original sources
PubMed1990

Circulating autoantibodies in multiple sclerosis.

By using indirect immunofluorescence method, we analyzed the presence of antinuclear, anticardiac, microsomal, parietal-cell, smooth-muscle and mitochondrial antibodies in sera of 33 patients with definite multiple sclerosis (MS), without clinical evidence of associated autoimmune disorder, and 14 patients with other neurological disorders (OND). In MS patients, the prevalence of both organ-specific and non-organ-specific antibodies was significantly higher (p less than 0.05) than in OND patients. In both groups, the titers of circulating antibodies were low. The presence of low levels of autoantibodies in sera of MS patients might be the result of immunodysregulation in MS.

Adult↗
PubMed1989

Psychiatric disorders associated with corticosteroid therapy.

Psychiatric disorders accompanying corticosteroid therapy are reported. They are much more frequently encountered than is generally believed. Moreover, they seem to correlate with the dosage applied. For more convenient clinical approach, we suggest classification of the disorders into four groups. The authors report two of their cases suffering from multiple sclerosis with associated steroid-induced psychosis. Besides the review of etiological mechanisms, the approach to treatment of psychiatric complications induced by steroid therapy is also suggested.

Adrenocorticotropic Hormone↗
PubMed1976

Comparative analysis of the therapy of acute transverse myelitis.

Three methods of treatment of acute transverse myelitis are presented. The first group of 16 patients were treated with antibiotics (average age 32.1). Three patients died, 11 remained unrecovered, while in two cases remarkable improvement was recorded. The second group of 15 patients, whose average age was 32.4, were treated with corticosteroid per os or instrumuscularly. Four of the patients died (three of them with ascendent course of disease), there was no change in five cases, while marked improvement ("cured" and "walking with assistance") was recorded in the remaining six cases. The third group of ten patients, eight women two men, ranging from 15 to 47 years of age (average age 26.9) was treated with methylprednisolone acetate intrathecally. Five patients were practically cured after 3 to 4 weeks. Two patients were cured to an extent that they could walk with assistance. In two cases no improvement was recorded, while one of the patients, who in addition suffered from serum myelitis, died of bilateral bronchopneumonia. In all these cases the drug was administered comparatively late, on the 6th or 7th day ofthe disease.

Acute Disease↗