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Biomedical subjects

Z Seidl

Publications and source records attributed to Z Seidl.

27 records · Page 2Linked to original sources

[Transient ischemic attacks (TIA) from the viewpoint of the clinical neurologist].

A transient ischaemic attack (TIA) is a cerebrovascular attack the clinical symptomatology of which is restored to normal within 24 hours. Minor haemorrhages, epilepsy, hypoglycaemia, migraine and even peripheral neuropathies can be mistaken for TIA. CT examination indicates in a considerable percentage of examined subjects encephalomalacia. The term TIA should be reserved for ischaemic attacks, where after regression of the clinical symptomatology within 24 hours no structural changes are found.

Humans↗

[Cerebral ischemic infarct in computer tomography imaging in the diagnosis of transient ischemic attacks].

The term transient ischaemic attack (TIA) does not correspond to findings of new examination methods and is rather a matter of convention. The authors examined 19 patients with the diagnosis of TIA by CT and found in five a cerebral infarction. The dependence of cerebral infarction in TIA on age, sex, risk factors (hypertension, diabetes) and the duration of clinical symptomatology was not significant.

Cerebral Infarction↗

[Fenestration of the anterior cerebral artery. Personal observation].

The authors demonstrate a patient with fenestration of the anterior cerebral artery. The fenestration is in the horizontal portion of the anterior cerebral artery (A1). Its embryonic origin and clinical importance arouse discussion. The paper reviews the literature on the subject.

Aged↗

[Diagnosis of tuberous sclerosis using computer tomography].

The authors examined 16 patients with tuberous sclerosis by computed tomography. In all patients calcifications were revealed, in the majority with a subependymal location, in 10 patients a medium severe hydrocephalus, in four a vaguely defined hypodensity, in two patients true tumours (astrocytomas). In six patients the clinical symptoms were atypical; in those instances computed tomography makes diagnosis of tuberous sclerosis possible. These findings are supplemented by data from the literature.

Adolescent↗

[Diagnosis of brain abscess using computer tomography].

The author examined 29 patients with the diagnosis of brain abscess by computed tomography (CT). In 28 instances the CT finding visualized a hypodense formation with an annular colouration which became more marked after administration of the contrast substance. In one patient the abscess was a hyperdense homogeneous focus. The pathological formation always behaved expansively with the surrounding oedema. The CT findings were correlated with other examination techniques (electroencephalography, cerebral angiography, cerebral scintigraphy). Visualization of the brain abscess on CT is not specific for this diagnosis. The same picture may be caused by a brain metastasis, glioma, ischaemia, an absorbing haematoma. Substrate diagnosis is not possible without a detailed case-history, clinical examination, laboratory examination and other examination methods. After introduction of CT diagnosis the mortality of patients with brain abscesses declined markedly.

Adolescent↗

Hemiparetic forms of cerebral palsy in relation to epilepsy and mental retardation.

Fifty-one children with hemiparetic cerebral palsy underwent clinical, EEG and CT examinations to assess mental performance, laterality of CP and incidence of epilepsy, 80 per cent of the children had epileptic abnormalities on EEG, but less than half had clinical signs of epilepsy. Clinical paroxysms were more frequent in those with right-sided hemiparesis. Focal or epileptic EEG changes were usual in those with right-hemisphere involvement, but unless clinical paroxysms developed, these had no bearing on mental performance. Lower IQ was found in the patients with clinical epilepsy--in nearly all cases with left-sided hemiparesis and in half of those with right-sided hemiparesis.

Adolescent↗

MRI--diagnostic and follow-up tool for microprolactinomas.

Magnetic resonance imaging is a method of choice for the diagnosis of microprolactinomas. Using a Phillips Gyroscan NT 15 (1.5 T), 42 patients whose clinical history and serum prolactin levels were compatible with the diagnosis of prolactinomas were examined. Four patients (3 male and 1 female) with macroadenoma were investigated and excluded, while microprolactinoma was found in the other 38 (32 female and 6 male) patients. Imaging features were similar in all microprolactinomas--hypointensity up to 10 mm in size in T1 weighted images, only sometimes, in the case of a cystic or a hemorrhagic component, also registered in T2 weighted images. Deviation of the pituitary stalk was present in 19 of the 38 patients (16 with microprolactinoma, 3 without any detectable lesion). Convex upper limit of the gland was demonstrated in 17 subjects (16 microprolactinomas, 1 without detectable lesion). Pituitary adenoma is not the only cause of raised serum prolactin level. This can be a consequence of medication, spinal cord tumor, compression of the pituitary stalk, hypothyroidism or a lesion in dermatomes T3 to T5 (mammary gland level). Results from imaging must always be assessed in the light of the patient's clinical history and biochemical parameters.

Adenoma↗