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PubMed · 10047512

Phage-display technology--finding a needle in a vast molecular haystack.

D J Rodi·L Makowski
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Abstract

Screening of phage-displayed libraries of proteins and peptides has, for nearly a decade, proven to be a highly effective method for finding much needed 'needles' in a vast molecular 'haystack'. Over the past year, it has been used to solve an increasing diversity of problems, including identification of binding motifs for much smaller targets and the use of novel screening methods to identify chemical activities.

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Bacteriophage M13BacteriophagesBiotechnologyData DisplayGene LibraryModels, MolecularMolecular MimicryPeptide LibraryViral ProteinsVirus ReplicationJournal ArticleReview

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D J Rodi, L Makowski. 1999. Phage-display technology--finding a needle in a vast molecular haystack.. https://doi.org/10.1016/s0958-1669(99)80016-0

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Bacteriophage M13↗