PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 10068984

[Ceftriaxone-induced cholelithiasis].

M Maccherini·G Borlini·M Branchi·C Barbonetti·P Moretti·G Bonora
View original source ↗Export metadata ↓

Abstract

The formation of biliary sludge and cholelithiasis after ceftriaxone administration is not uncommon. Prompt resolution of sludge has been demonstrated with discontinuation of the drug. Despite this, cholecystectomy has been performed in symptomatic patients. Ceftriaxone is popular drug in pediatrics, but the complication is not widely appreciated in the gastroenterology and surgical literature. For this adverse effect and for cost ceftriaxone should be used with more caution. We describe two cases of children with ceftriaxone induced cholelithiasis.

Explore related subjects

CeftriaxoneCephalosporinsChildCholelithiasisFemaleFollow-Up StudiesHumansMaleTime FactorsUltrasonographyCase ReportsJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

M Maccherini, G Borlini, M Branchi, C Barbonetti, P Moretti, G Bonora. [Ceftriaxone-induced cholelithiasis].. https://pubmed.ncbi.nlm.nih.gov/10068984/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2006

Skull base osteomyelitis presenting as Villaret's syndrome.

This report documents a 47-year-old male who developed acute deficits of the IX, X, XI, XII cranial nerves and Horner's symptoms, consistent with Villaret's syndrome. Neuroimaging studies demonstrated an osteolytic lesion in the skull base involving the clivus and jugular foramen. The patient recovered after the antibiotic treatment for proteus mirabilis infection. We suggest that Villaret's syndrome can be a rare presentation of skull base osteomyelitis.

Ceftriaxone↗
PubMed2004

Isolation of Salmonella enterica serotype choleraesuis resistant to ceftriaxone and ciprofloxacin.

Salmonella enterica serotype choleraesuis (S choleraesuis) usually causes systemic infections in man that need antimicrobial treatment. We isolated a strain of S choleraesuis that was resistant to ceftriaxone and ciprofloxacin from a patient with sepsis. Ciprofloxacin resistance was associated with mutations in gyrA and parC, whereas the ampC gene (bla(CMY-2)), responsible for ceftriaxone resistance, was carried by a transposon-like mobile element. This element was found inserted into finQ of a potentially transmissible 140 kb plasmid, with an 8 bp direct repeat flanking the junction regions. The appearance of this resistant S choleraesuis is a serious threat to public health, and thus constant surveillance is warranted.

Ceftriaxone↗