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PubMed · 10203791

The subapical compartment: a novel sorting centre?

S C van IJzendoorn·D Hoekstra
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Abstract

Establishment of plasma membrane polarity involves numerous intracellular sorting events. In the past few years, it has become apparent that there is a subapical, non-Golgi compartment located in the hub of the sorting pathways involved. This 'subapical compartment', which probably consists of a heterogeneous subset of functionally distinct domains related to endosomes, contains some well-characterized components involved in polarity-dependent sorting and targeting of proteins and lipids. This article discusses the evidence supporting the existence of such a compartment, its biogenesis and its role in cell polarity.

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AnimalsBiological TransportCell CompartmentationCell LineCell PolarityDogsEndocytosisEndosomesGolgi ApparatusMembrane LipidsMembrane ProteinsMicrotubulesModels, BiologicalJournal Article

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S C van IJzendoorn, D Hoekstra. 1999. The subapical compartment: a novel sorting centre?. https://doi.org/10.1016/s0962-8924(99)01512-3

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