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Interhemispheric interactions analyzed by coherence during flexor spasms.

H Otsubo·M Steinlin·A Shirasawa·P A Hwang·R Munn·V Jay·H J Hoffman
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Abstract

OBJECTIVE: We used coherence analysis to test for leading discharges on an ipsilateral right mesial temporal lesion in a 5 year old boy with flexor spasms. METHOD: Digital EEG analysis with video-EEG telemetry was performed preparatory to epilepsy surgery. RESULTS: Study of 10 spasms with head drop and subsequent flexion of both arms demonstrated an interhemispheric time lag with secondary bilateral synchrony, with a mean difference of 17 ms. The right hemisphere led. After a lesionectomy with resection of epileptic regions (performed with electrocorticographical guidance), the patient has been seizure-free for 4 years. Pathology confirmed a low-grade mixed glioma and cortical dysgenesis. CONCLUSION: The coherence analysis demonstrated a pathway of secondary generalization, confirming that the lesional side was leading during ictal generalized discharges in flexor spasms.

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BrainChild, PreschoolElectroencephalographyHumansMaleMonitoring, PhysiologicSpasms, InfantileTime FactorsCase ReportsJournal Article

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H Otsubo, M Steinlin, A Shirasawa, P A Hwang, R Munn, V Jay, H J Hoffman. 1999. Interhemispheric interactions analyzed by coherence during flexor spasms.. https://doi.org/10.1016/s1388-2457(98)00024-8

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