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PubMed · 10421519

A new model for improved gastrectomy drainage.

Abstract

Slow waves in isolated jejunal segments have been shown, in at least two studies, to have an increased percentage of neither prograde nor retrograde progression. Instead the pattern has been characterized as "nonpropagating" by Johnson and Sarna et al., and "chaotic" by others. We compared gastric drainage produced by a Roux-Y created with a single transection, with gastric drainage produced by a Roux-Y created in a jejunal segment isolated between two transections. Theoretically, this avoids the retrograde slow waves produced by a single transection. Ten dogs of either gender were divided into two groups of five. One group was given a truncal vagotomy, hemigastrectomy, and a standard Roux-Y drainage with a single jejunal transection; the other five were given the same operation with a distal jejunal transection and anastomosis 25 cm beyond the jejunojejunostomy (thus creating the Roux-Y in an isolated segment). In the approximate 50-day follow-up, 3 of 5 animals with standard preparations developed considerable difficulty in maintaining nutrition and developed hugely dilated stomachs. Animals with stomachs drained by the isolated jejunal segment Roux-Y had less difficulty maintaining nutrition and experienced minimal gastric dilatation. These findings were confirmed by upper gastrointestinal series at 2 weeks and at autopsy. In conclusion, this study shows that gastric drainage following truncal vagotomy and hemigastrectomy is enhanced by a Roux-Y created in an isolated jejunal segment.

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P Rizzo, T Oweis, L Penman. A new model for improved gastrectomy drainage.. https://doi.org/10.1080/089419399272575

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Anastomosis, Roux-en-Y↗

Myoelectric activity and motility of the Roux limb after cut or uncut Roux-en-Y gastrojejunostomy.

AIM: To explore the mechanisms of uncut Roux-en-Y gastrojejunostomy, which is used to decrease the occurrence of Roux stasis syndrome. METHODS: The changes of myoelectric activity, mechanic motility and interstitial cells of Cajal (ICC) of the Roux limb after cut or uncut Roux-en-Y gastrojejunostomy were observed. RESULTS: When compared with the cut group, the amplitude (1.15 +/- 0.15 mV vs 0.48 +/- 0.06 mV, P < 0.05) and frequency (14.4 +/- 1.9 cpm vs 9.5 +/- 1.1 cpm, P < 0.01) of slow waves and the incidence (98.2% +/- 10.4% vs 56.6% +/- 6.4%, P < 0.05) and amplitude (0.58 +/- 0.08 mV vs 0.23 +/- 0.06 mV, P < 0.01) of spike potential of the Roux limb in the uncut group were significantly higher. The migrating myoelectric complexes (MMC) phase III duration in the uncut group was significantly prolonged (6.5 +/- 1.1 min vs 4.4 +/- 0.8 min, P < 0.05), while the MMC cycle obviously shortened (42.5 +/- 6.8 vs 55.3 +/- 8.2 min, P < 0.05). Both gastric emptying rate (65.5% +/- 7.9% vs 49.3% +/- 6.8%, P < 0.01) and intestinal impelling ratio (53.4% +/- 7.4% vs 32.2% +/- 5.4%, P < 0.01) in the uncut group were significantly increased. The contractile force index of the isolated jejunal segment in the uncut group was significantly higher (36.8 +/- 5.1 vs 15.3 +/- 2.2, P < 0.01), and the expression of c-kit mRNA was significantly increased in the uncut group (0.82 +/- 0.11 vs 0.35 +/- 0.06, P < 0.01). CONCLUSION: Uncut Roux-en-Y gastrojejunostomy may lessen the effects of operation on myoelectric activity such as slow waves, spike potential, and MMC, decrease the impairment of gastrointestinal motility, and remarkably increase the expression of c-kit mRNA.

Anastomosis, Roux-en-Y↗