PubMed · 10715332
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H Seymour, R Given-Wilson, L Wilkinson, J Cooke. Resolving breast microcalcifications.. https://doi.org/10.1148/radiographics.20.2.g00mc37307
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This study was undertaken to determine the discriminating cytological features between nonhigh-grade duct carcinoma in situ (NHGDCIS) and benign breast lesions and to determine any histological characteristics which would influence the cytological categorization. Smears of 12 each of histologically confirmed NHGDCIS and benign breast lesions were reviewed with regard to cellularity, cell discohesion, nuclear atypia, crowding of cells, tubule formation, necrosis, and presence of bare atypical nuclei and regular bare bipolar nuclei, and statistically analyzed. Architectural pattern, presence of necrosis, and the size of the lesion assessed at histological examination were compared with the initial cytological categorization. NHGDCIS lesions showed more cell discohesion (P = 0.04), bare atypical nuclei (P = 0.05), necrosis (P = 0.03), and sparse bare bipolar nuclei (P = 0.02) than benign lesions. These differences were statistically significant. Cellularity (P = 0.8), nuclear atypia (P = 0.06), crowding of cells (P = 0.1), and tubule formation did not show a significant difference. Six (out of six lesions) with a solid architectural pattern and six (of seven) with necrosis could be cytologically categorized as suspicious or malignant. Size of the lesion did not influence this. We conclude that cell discohesion, bare atypical and bare bipolar nuclei, and necrosis are discriminating features between NHGDCIS and benign breast lesions and NHGDCIS lesions with a solid architectural pattern and necrosis are more likely to be satisfactorily categorized cytologically.
For the last 7 years, D.H. Lalonde has added the No Vertical Scar breast reduction to his armamentarium of reduction techniques. This operation is almost the same as the inferior pedicle T scar reduction. However, a small modification of the Wise pattern permits the deletion of the vertical portion of the T scar. The first 14 years of the Dr. Lalonde's practice consisted almost exclusively of the T scar reduction. He currently uses the Vertical reduction, the T reduction, and in over 150 cases, the No Vertical Scar reduction. Indications, technical details, and results of the No Vertical Scar reduction are discussed here.
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