Gap junctional intercellular communication and carcinogenesis.

S Sulkowski; M Sulkowska; E Skrzydlewska

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PubMed · 10721262

Gap junctional intercellular communication and carcinogenesis.

S Sulkowski·M Sulkowska·E Skrzydlewska

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Abstract

Intercellular communications are indispensable for the maintenance of homeostasis in the multicellular organisms. Gap-type junctions are one of the most common and perhaps most interesting intercellular connections. Of various communication systems gap junctional intercellular communication is the only means for cells to directly exchange signals. Substantial progress has recently been made in the studies on the role of gap junctions both in experimental and human tumorigenesis. The present study is a review of the potential mechanisms associated with gap junctional cellular communication included in non-genotoxic tumorigenesis.

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Animals Cell Adhesion Molecules Cell Communication Connexins Gap Junctions Humans Neoplasms Editorial Research Support, Non-U.S. Gov't Review

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S Sulkowski, M Sulkowska, E Skrzydlewska. 1999. Gap junctional intercellular communication and carcinogenesis.. https://pubmed.ncbi.nlm.nih.gov/10721262/

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