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PubMed · 10811562

Calculating bone-lead measurement variance.

A C Todd
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Abstract

The technique of (109)Cd-based X-ray fluorescence (XRF) measurements of lead in bone is well established. A paper by some XRF researchers [Gordon CL, et al. The Reproducibility of (109)Cd-based X-ray Fluorescence Measurements of Bone Lead. Environ Health Perspect 102:690-694 (1994)] presented the currently practiced method for calculating the variance of an in vivo measurement once a calibration line has been established. This paper corrects typographical errors in the method published by those authors; presents a crude estimate of the measurement error that can be acquired without computational peak fitting programs; and draws attention to the measurement error attributable to covariance, an important feature in the construct of the currently accepted method that is flawed under certain circumstances.

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Analysis of VarianceBiometryBone and BonesCadmium RadioisotopesFluorescenceHumansLeadX-RaysJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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A C Todd. 2000. Calculating bone-lead measurement variance.. https://doi.org/10.1289/ehp.00108383

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