Translational frameshift sites within bacteriophage lambda genes rexA and cI.

S Hayes; H J Bull

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PubMed · 10824855

Translational frameshift sites within bacteriophage lambda genes rexA and cI.

S Hayes·H J Bull

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Abstract

Phage lambda's cI-rexA-rexB operon displays an intriguing example of regulation by an unexplained mechanism of polarity. We have identified three potential -1 translational frameshift sites and present a model for translational frameshift suppression by lambda's CI repressor as a mechanism of regulating operon polarity, implying an additional role for CI self-regulation.

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Bacteriophage lambda Base Sequence DNA-Binding Proteins Frameshifting, Ribosomal Gene Expression Regulation, Viral Genes, Viral Lysogeny Models, Genetic Mutation Operon Phenotype RNA, Viral Repressor Proteins Viral Nonstructural Proteins Viral Proteins Viral Regulatory and Accessory Proteins Virus Activation Journal Article Research Support, Non-U.S. Gov't

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S Hayes, H J Bull. 1999. Translational frameshift sites within bacteriophage lambda genes rexA and cI.. https://pubmed.ncbi.nlm.nih.gov/10824855/

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