PubMed · 10869150
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P Gautam, S R Phadke. 2000. Fetal brain disruption sequence.. https://pubmed.ncbi.nlm.nih.gov/10869150/
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INTRODUCTION: Sagittal synostosis has been found to occur in families at a low frequency. All previous reports of sagittal synostosis in twins have been of males. CASE REPORT: We now report a case of female twins concordant for sagittal synostosis. CONCLUSION: Our hopes are that this information will further our understanding of the genetics of sagittal synostosis not only in single births but also in that of twins.
Sagittal synostosis is the most common form of craniosynostosis (i.e., premature fusion of cranial sutures). Sagittal synostosis, which is the premature fusion of the sagittal suture, occurs in 56% to 58% of all reported cases of craniosynostosis. This article describes calvarial vault remodeling, the procedure of choice at Children's Hospital Los Angeles for surgical intervention to correct sagittal synostosis. Perioperative interventions to minimize patients' risks and maximize benefits are explained. A case study is presented to describe the experience of one patient and his family members.