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PubMed · 10881663

[Study of CATCH 22: genetic aspects].

V G Antonenko·V I Ivanov·L M Konstantinova·L Ia Levina·V A Mglinets
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Abstract

Introducing molecular genetic techniques into clinical practice has made it possible to detect del 22q11.2, an etiological factor for congenital cardiovascular diseases in CATCH 22. The authors' complex (clinical, syndromological, molecular genetic, and computed) approach to examining this group of syndromes has enabled patients at high risk for CATCH 22 to be identified. A list of gene candidates responsible for manifestations of CATCH 22 and data on how pathological phenotypes are developing in model objects are presented.

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Abnormalities, MultipleChromosome DeletionChromosomes, Human, Pair 22Cleft PalateGenetic MarkersHeart Defects, CongenitalHumansHypocalcemiaMaxillofacial AbnormalitiesPhenotypeProteinsThymus GlandEnglish AbstractJournal ArticleReview

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V G Antonenko, V I Ivanov, L M Konstantinova, L Ia Levina, V A Mglinets. 2000. [Study of CATCH 22: genetic aspects].. https://pubmed.ncbi.nlm.nih.gov/10881663/

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