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PubMed · 10894975

Delayed generalized allergic reactions to corticosteroids.

A J Bircher·P Bigliardi·T Zaugg·S Mäkinen-Kiljunen
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Abstract

A 37-year-old patient presented with a severe allergic local reaction upon inhalation of budesonide for asthma. Skin tests were positive for budesonide and amcinonide (group B) and elicited a strong local reaction and a disseminated macular exanthema. Corticosteroids from other groups were well tolerated. A 38-year-old male patient had first an allergic contact dermatitis to topically applied prednisolone acetate and then a disseminated eczematous exanthema upon oral intake of prednisone. A delayed-type sensitization to corticosteroids from group A such as hydrocortisone, prednisone and tixocortol pivalate was identified. A detailed diagnosis in patients with allergic reactions to corticosteroids is crucial with regard to their use in emergency therapy.

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Adrenal Cortex HormonesAdultAsthmaBudesonideDermatitisDrug EruptionsHumansHypersensitivity, DelayedMalePatch TestsPrednisoloneSkinCase ReportsJournal Article

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BibTeXRIS

A J Bircher, P Bigliardi, T Zaugg, S Mäkinen-Kiljunen. 2000. Delayed generalized allergic reactions to corticosteroids.. https://doi.org/10.1159/000018408

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